1 citations
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January 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” This study found that while PRP or nanofat injections improved scarred tissue texture in secondary cicatricial alopecia, they did not significantly enhance hair restoration outcomes compared to hair transplantation alone.
June 2025 in “International Journal of Applied Pharmaceutics” In this experimental study on alopecia mice, PRP-exosome treatment was reported to significantly improve hair follicle density and the anagen:telogen ratio compared to 5% minoxidil.
June 2025 in “International Journal of Applied Pharmaceutics” This study developed a testosterone-induced androgenetic alopecia model in BALB/c mice, finding that a 0.075 ml testosterone injection best replicated the dermal and hair follicle conditions of AGA patients, providing a promising tool for future drug testing and research into AGA therapies.
February 2025 in “Archives of Dermatological Research” Combining PRP with topical minoxidil is most effective for hair growth in androgenetic alopecia.
January 2025 in “Diagnostics” This study found that a new three-dimensional high-frequency ultrasound (3D-HFUS) can successfully visualize skin tumors and inflammatory hair diseases, offering promising noninvasive diagnostic and evaluation capabilities compared to traditional two-dimensional methods.
March 2024 in “Agriculture” The researchers reviewed the status, challenges, and future prospects of CRISPR/Cas9-mediated gene-editing technology in livestock breeding, noting its benefits and highlighting concerns about low efficiency in inserting foreign genes and off-target effects.
January 2022 in “International Journal of Medical Sciences” This study investigated the effects of cedrol on colorectal cancer and found that it inhibited cell proliferation and induced cell cycle arrest and apoptosis in cell models, while in vivo, it suppressed cancer progression and improved survival at a well-tolerated dose.
August 2022 in “International Journal of Molecular Sciences” This study found that lncRNA2919 negatively impacts hair follicle regeneration by decreasing follicle depth and density in a rabbit model, suggesting a regulatory role in the hair follicle cycle through DNA methylation.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
19 citations
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June 2020 in “Animals” This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.
13 citations
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May 2004 in “Dermatologic Surgery” This article outlines a method for achieving natural-looking hair direction and density in hair transplants using specific parting and incision techniques, without accelerating hair loss in the recipient area.
13 citations
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January 2013 in “Dermatologic Surgery” This survey estimates that the number of follicular units with "permanent" hair available for transplant varies based on hair density and projected male pattern baldness type, providing guidelines for realistic surgical goals.
29 citations
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April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
26 citations
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June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
13 citations
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July 2016 in “BMC Complementary and Alternative Medicine” In this study, topical application of Hominis Placenta significantly promoted hair regrowth and increased hair density in C57BL/6 mice, suggesting its potential as a treatment for alopecia.
2 citations
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January 2018 in “The Korea Journal of Herbology” In this study with C57BL/6 mice, SHJ extract was associated with increased hair growth and density, suggesting potential use in hair care cosmeceuticals, while also enhancing melanin production in melanoma cells.
87 citations
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July 2007 in “British Journal Of Nutrition” In this study, oral administration of Lactococcus lactis strain H61 to senescence-accelerated mice was linked to reduced bone density loss, less skin ulcer incidence, and reduced hair loss, along with altered immune responses.
27 citations
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September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
March 2026 in “Frontiers in Pharmacology” This study reviews new treatments for androgenetic alopecia, including cell-derived exosomes and investigational drugs, which show potential to improve hair density and quality but require more rigorous and standardized trials to confirm efficacy and safety.
4 citations
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January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
2 citations
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January 2023 in “BMC plant biology” This study found that root hair length and density in rice are controlled by distinct genomic regions, with 18 regions identified but no overlap between the traits.
1 citations
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January 2019 in “PubMed” This study found that transgenic mice expressing cgVEGF164 had increased hair follicle diameter and density, potentially linked to higher phosphorylation levels of ERK1/2, AKT1, and LEF1 proteins.
February 2026 in “International Journal of Nanomedicine” This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.
1 citations
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April 2023 in “Journal of Animal Science and Biotechnology” This study found that treating cashmere goat kids with melatonin significantly increased secondary hair follicle density, improving cashmere quality and yield, likely through mechanisms involving the MAPK signaling pathway.
May 2025 in “Journal of Craniofacial Surgery Open” This case study observed that high-intensity focused ultrasound treatment significantly improved hair density and reduced hair loss in a female patient with androgenetic alopecia, with no adverse events reported.
1 citations
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June 2018 in “Open Access Macedonian Journal of Medical Sciences” This report describes a case where previously poorly implanted hairs were successfully recycled through follicular unit extraction to improve hair density and patient satisfaction in androgenetic alopecia.
11 citations
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May 2019 in “BioMed Research International” The researchers reported that follicular unit hair transplantation achieved a mean graft survival rate of 80.67% and significantly improved patient and observer satisfaction in individuals with stable cicatricial alopecia from postsurgical scalp scarring.
12 citations
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April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
4 citations
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February 2022 in “International Journal of Cosmetic Science” This study found that watercress extract may help treat hair loss by increasing RSPO1 secretion and decreasing DKK1 secretion, improving hair thickness and density in clinical trials.
2 citations
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May 2018 in “PubMed” In this study, hair restoration using follicular unit extraction removed about 35% of donor area hair density, indicating a need for careful consideration of varying donor densities.