April 2026 in “Aesthetic Plastic Surgery” This study reported that a standardized hair transplantation procedure significantly improved both patient and surgeon satisfaction with aesthetic results for East Asian women with non-ideal facial proportions, achieving a natural-looking hairline without significant complications.
October 2024 in “Skin Research and Technology” In this study, extracorporeal shock wave treatment for female pattern hair loss resulted in significant increases in hair count and thickness in 20 women, with 85% of participants perceiving improvements in hair volume.
April 2024 in “Frontiers in endocrinology (Lausanne)” In this meta-analysis, researchers found that melatonin did not affect primary hair follicles or litter size in goats but was positively correlated with secondary follicle growth, suggesting potential relevance for studying hair growth mechanisms and human alopecia.
January 2024 in “Authorea (Authorea)” In this retrospective study of 1,415 male hair transplant patients, punch technology improvements for the FUE method were associated with an increased number of total grafts and multi-hair follicular units over time, making FUE a preferred choice for hair transplantation.
November 2023 in “Biology” This study investigated m6A RNA modification in hair follicle development, finding that Hycole rabbits displayed longer hair, higher primary hair follicle ratios, and thicker skin compared to Rex rabbits, while also identifying key differential genes and pathways involved in hair growth.
100 citations
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August 2008 in “American Journal Of Pathology” This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
74 citations
,
January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
43 citations
,
January 2016 in “Oxidative medicine and cellular longevity” This review discusses the biological effects and mechanisms of THSG in antiaging and related disease treatments but reports no new experimental findings.
30 citations
,
February 2023 in “Animals” This study suggests that the period from birth to 6 months is optimal for regulating secondary hair follicle development in cashmere goats, with specific growth factors potentially playing a regulatory role.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.
10 citations
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January 2024 in “Burns & Trauma” This meta-analysis found that ADSC-Exo therapy can enhance healing in both general and diabetic wounds by promoting neovascularization, improving epithelization and collagen fiber deposition, and reducing scar formation, suggesting significant potential for clinical and research applications.
9 citations
,
July 2024 in “JAAD reviews.” This review discusses the role of extracellular vesicles in dermatology for therapeutic, diagnostic, and prognostic purposes, highlighting the lack of validated findings and the necessity for more rigorous clinical trials.
4 citations
,
May 2024 in “Genes” Among Merino × Southdown cross sheep, this study found that certain variants of the KRT81 gene were associated with differences in fleece weight, but not with staple length or fibre diameter traits.
4 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
2 citations
,
June 2025 in “ACS Biomaterials Science & Engineering” This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.
2 citations
,
November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
2 citations
,
August 2023 in “Marine drugs” In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression.
2 citations
,
July 2022 in “Frontiers in Cardiovascular Medicine” This review discusses the pharmacological activities and mechanisms of forsythiasides, highlighting their potential therapeutic value, but reports no new clinical results.
2 citations
,
June 2022 in “Cosmoderma” This review discusses regenerative medicine's applications in dermatology, highlighting the need for quality clinical trials to optimize treatments like PRP, stem cells, and exosomes, and reports no new results.
August 2026 in “Plastic & Reconstructive Surgery Global Open” In this study, researchers observed that hybrid secretomes most effectively stimulated proliferation and stem cell markers for hair regeneration in hamster skin, while human secretomes strongly activated the Wnt/β catenin pathway, suggesting different underlying mechanisms among the tested formulations.
This study found that single-born cashmere goats had higher birth weights, pre-weaning growth rates, and superior cashmere production attributes compared to twin-born goats, despite twin-born goats achieving compensatory growth post-weaning.
May 2026 in “Microorganisms” This study found that individuals with seborrheic alopecia had significant disruptions in their scalp microbiome, marked by imbalances in certain bacteria and fungi, and that a 12-week herbal shampoo intervention helped restore microbial diversity and improve clinical symptoms.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
February 2026 in “Trends in Sciences” In a testosterone-induced mouse model, this study found that exosomes from injectable Platelet-Rich Fibrin (i-PRF) significantly reduced inflammation, oxidative stress, and apoptosis, while enhancing hair regeneration, with the greatest improvements seen when combined with minoxidil, suggesting potential as a novel treatment for androgenetic alopecia.
January 2026 in “Cosmetics” This study highlights emerging regenerative strategies, such as stem cell-derived therapies and machine learning tools, that may advance hair loss treatment beyond traditional methods by promoting follicle regeneration and offering personalized care.
January 2026 in “Research” This review discusses advanced biomedical technologies, such as nanotechnology and stem cell-based approaches, for treating androgenetic alopecia, detailing their benefits, current applications, and challenges, without reporting new experimental results.
December 2025 in “Medical Sciences” This study critically reviewed recent evidence (2020–2025) on treatments like platelet-rich plasma, photobiomodulation, stem cells, and exosomes for androgenetic alopecia, finding emerging but limited efficacy data and emphasizing the need for standardized protocols to enhance transparency and patient safety.
November 2025 in “JPRAS Open” This study found that while exosome therapy shows promise for treating AGA, AA, and CIA, its integration into routine practice will depend on rigorous clinical trials and standardized manufacturing and regulatory practices to ensure safety and reproducibility.
July 2025 in “Biotechnology and Bioprocess Engineering” This study found that Camellia japonica seed extract promotes hair growth by preventing premature cellular senescence and enhancing the activity of hair follicle stem cells in cases of pattern hair loss.