2 citations
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January 1987 in “PubMed” This study reported three related cases of woolly hair syndrome transmitted as a dominant autosomal trait, characterized by fine, frizzy hair and general hair thinning.
December 2024 in “Biomedical & Pharmacology Journal” In this study, researchers developed and assessed two polyherbal hair tonic formulations, finding that Hair Tonic A containing 10% white tea extract improved hair thickness, manageability, and anti-frizz properties, particularly for blonde and black hair, while demonstrating greater stability compared to Hair Tonic B.
This study analyzes the application of a new hair serum incorporating natural ingredients like Aloe vera and ginger, finding it potentially beneficial for managing hair frizz, improving smoothness, and preventing damage without significant adverse reactions.
This study found that a blend of low- and high-molecular weight hyaluronic acid significantly improved penetration into the hair cortex compared to individual HA types, reducing frizz and increasing hair elasticity and water content, as measured by Confocal Raman Spectroscopy.
January 2026 in “International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences” This study developed and tested an herbal hair serum containing aloe vera, hibiscus, rose extract, ginger, amla, argan oil, and vitamin E, finding it to be safe, non-irritating, and effective in improving hair shine, reducing frizz, and enhancing manageability.
September 2025 in “Acta Scientific Pharmaceutical Sciences” This paper examines the rising popularity and potential benefits of rice water for hair care, noting that while it contains beneficial compounds like inositol that may increase hair strength and decrease frizz, there is still no definitive scientific proof of its efficacy.
December 2024 in “Deleted Journal” This review highlights that flaxseed, due to its high levels of antioxidants and essential fatty acids, may improve hair texture, reduce frizz, and support hair growth, though more clinical studies are needed to confirm the best formulations and effects.
July 2026 in “Open Minds International Journal” This review suggests that multifunctional cosmetic systems, particularly HIVEN Curl Code ®, may help control frizz and maintain curl definition in highly curly hair by utilizing various conditioning and biofunctional ingredients.
January 2022 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This article presents an overview of uncombable hair syndrome, emphasizing its clinical and molecular characteristics and noting systemic manifestations such as neuropsychiatric, ophthalmic, and cardiopulmonary issues.
December 2023 in “University of Southern Denmark Research Portal (University of Southern Denmark)” This case report discusses a 9-year-old boy diagnosed with uncombable hair syndrome, a rare hair shaft anomaly characterized by blond, frizzy, and unruly hair. The diagnosis was prompted by the boy's mother, who suspected the condition after reading a medical paper on hair shaft anomalies. Molecular genetics confirmed the diagnosis. The report highlights the role of digital access in raising awareness of rare conditions among patients and their families.
January 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” This review highlights the increasing use of herbal cosmetics for maintaining healthy hair growth and preventing premature greying, influenced by rising living standards and interest in personal care.
February 2023 in “JEADV Clinical Practice” This case report describes a girl with uncombable hair syndrome who showed significant improvement in hair combability and growth rate after two cycles of oral biotin supplementation.
September 2017 in “Pediatric Dermatology” This source provides no abstract, offering no results or conclusions on a case involving a 14-year-old boy with abrupt-onset hair changes presented in a photo quiz format in Pediatric Dermatology.
26 citations
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October 1999 in “Archives of Dermatology” This discussion suggests that acquired progressive kinking of hair in androgen-dependent scalp areas may indicate the early stages of androgenetic alopecia with a poor prognosis, but it offers no new clinical findings.
2 citations
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March 2024 in “Pediatric Dermatology” This case report described two siblings with uncombable hair syndrome characterized by unique hair features, and identified a new pathogenic variant in the PADI3 gene (c.1374dup; p. Val459ArgfsTer15) not previously documented.
2 citations
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October 2018 in “Skin appendage disorders” This case report describes a 2-year-old boy with uncombable hair syndrome-like hair changes that resolved spontaneously after 9 months, with genetic analysis revealing a PLCD1 gene variant.
40 citations
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June 2013 in “Journal of cosmetic dermatology” This review discusses the widespread use of Brazilian keratin treatments and notes that many contain formaldehyde, marketed as safe despite potential safety concerns, but reports no new clinical results.
December 2020 in “Dermatology practical & conceptual” Trichoscopy helped diagnose a teenage girl's hair loss as monilethrix.
December 2022 in “American journal of medical genetics. Part A” This case report describes an instance of autosomal recessive uncombable hair syndrome caused by maternal uniparental disomy of chromosome 1.
1 citations
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July 1935 in “Nature” This study found super-contraction in the guard hairs of fur-bearing animals, likely due to oxidation in living animals, primarily affecting white and red foxes without prior heat or chemical treatment.
February 2022 in “Cosmetic Dermatology” This review discusses the physiology of hair and various grooming and camouflage techniques, but reports no new clinical results; the authors note the complexity of cleaning hair and effects of different detergents.
47 citations
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November 2007 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses how various factors, including cosmetic procedures and scalp conditions, can damage hair, but highlights the availability of products to improve hair health; it reports no new empirical results.
June 2025 in “British Journal of Dermatology” This systematic review found that licensed hair gloss products in the UK provide significant cosmetic benefits like improved shine and smoothness, but 18% contain harmful additives, highlighting the need for stricter regulations and patient education on product safety.
January 2025 in “INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT” This abstract highlights the increasing significance of herbal hair conditioners, which blend traditional plant-based ingredients with modern hair care needs, offering benefits like nourishing and protecting hair without harsh chemicals, and meeting consumer preferences for eco-friendly, organic products in the beauty industry.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights flaxseed's potential as a natural hair care ingredient due to its moisturizing, strengthening, and nutritional qualities attributed to its high antioxidant and essential fatty acid content; however, further clinical studies are needed to optimize formulations and assess long-term effects.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of flaxseed as a natural hair care ingredient, noting its moisturizing, strengthening, and nutritional properties that may improve hair health and texture, though more clinical studies are needed to confirm these benefits.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study outlines the potential benefits of a formulated herbal hair serum containing ingredients like black seed, ginger, and almond oil, highlighting its ability to improve scalp health, promote hair growth, reduce hair fall, and enhance hair shine and manageability.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that a formulated herbal hair serum containing ingredients like Nigella Savita, ginger, and vitamin E shows significant potential for promoting hair growth, reducing hair fall, and improving manageability, suggesting its promise as a natural hair care product pending further clinical evaluation.
December 2023 in “Deleted Journal” This research project focused on developing a herbal hair serum using natural ingredients like Flaxseed, Aloe Vera, and Vitamin E, aimed at addressing issues like hair fall and dandruff while promoting overall hair health. Results of the study are not reported.
August 2021 in “International Journal of Research in Dermatology” This article reviews various hair straightening methods, discussing their mechanisms and potential effects on hair, but it reports no new clinical results.