research Finding Long-COVID: Temporal Topic Modeling of Electronic Health Records from the N3C and RECOVER Programs
Long-COVID has diverse, long-term health impacts, especially in young people.
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research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome
Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
research Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture
Autophagy is important for human hair growth and health.
research Development and Validation of a Procedure for the Determination of Minoxidil in Hair-Regrowth Formulations Using Two Variants of Capillary Zone Electrophoresis
A method was created in 2005 to identify minoxidil, a hair growth ingredient, in products using two types of capillary zone electrophoresis, and it found that most products had about 2% minoxidil.
research A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control
Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Treatment of Hirsutism and Acne with Cyproterone Acetate
Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research An Attempt to Assess the Magnitude of Endogenous Androgen Production in a Case of the Adrenogenital Syndrome
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research Differential Activity of 2-Methylene-19-Nor Vitamin D Analogs on Growth Factor Gene Expression in Rhino Mouse Skin and Comparison to All-Trans Retinoic Acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research Development and Characterization of Minoxidil-Loaded Liposomal System for Delivery to Pilosebaceous Units
Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Hormone Therapy in Acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Spontaneous Improvement of Cronkhite-Canada Syndrome in a Postpartum Female
A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
research Association Between Scalp Laxity, Elasticity, and Glidability and Donor Strip Scar Width in Hair Transplantation and a New Elasticity Measuring Method
Higher scalp elasticity leads to wider scars after hair transplantation; a new method to measure elasticity may help predict scar size.
research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment
Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.
research The Pediatric Origins of Polycystic Ovary Syndrome
Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
research Genetic Variation at the MC1R Locus and the Time Since Loss of Human Body Hair
Humans lost body hair relatively recently in evolution.
research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
research Platelet-Rich Plasma for Androgenetic Alopecia
PRP injections improve hair thickness for baldness.
research What Do We Know About Phytotherapy of Benign Prostatic Hyperplasia?
Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
research Wetting Behavior of Human Hair Fibers
Human hair's ability to get wet is complex and can change with treatments, damage, and environment.
research Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia
Finasteride-loaded nanoparticles may help treat alopecia.
research Preparation and Characterization of Beta-Sitosterol-Loaded Nanostructured Lipid Carriers for Butter Enrichment
Researchers made a special butter with added betasitosterol that could be healthier for the heart and stayed good for three months.
research Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-Induced Inflammation and Oxidative Stress
Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
research Formulation and In Vitro Evaluation of Polymeric Enteric Nanoparticles as Dermal Carriers with pH-Dependent Targeting Potential
Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
research Evidence-Based Approach to Cutaneous Hyperandrogenism in Women
The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
research Photobiomodulation of Human Dermal Fibroblasts In Vitro: Decisive Role of Cell Culture Conditions and Treatment Protocols on Experimental Outcome
Different lab conditions and light treatment methods change how human skin cells respond to light therapy.