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Removing part of the vitamin D receptor stops vitamin D from working properly.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

The Rotterdam Study aims to understand various diseases in older adults.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Having enough iron improves the effectiveness of a specific hair loss treatment in women.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.