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April 2021 in “ACS omega” Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
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September 2020 in “Pharmaceutics” Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
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March 2018 in “Current Drug Delivery” The document reviewed various topical delivery systems for finasteride, a compound used to treat androgenetic alopecia (male pattern baldness), to mitigate the systemic side effects associated with its oral use, such as sexual disorders. The literature indicated that topical formulations, including polymersomes, vesicular nanocarriers, liposomes, and gels, could enhance localized skin penetration of finasteride. Notably, finasteride liposomal gel with 2% methyl cellulose and a gel system with poloxamer P407 showed the highest permeation rates, with flux values of 28.4 ± 1.3 µg/cm²h and 23.1 ± 1.4 µg/cm²h, respectively. The study suggested that future research should explore additional topical delivery techniques like microneedles, nanoemulsions, and emulsifier-free formulations.
14 citations,
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January 1987 in “PubMed” Low-dose spironolactone is safe and effective for treating hirsutism.
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