research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
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research Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function
Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
research A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation
A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Discovery of Genes and Proteins Possibly Regulating Mean Wool Fibre Diameter Using cDNA Microarray and Proteomic Approaches
Researchers identified genes and proteins that may influence wool thickness in sheep.
research Loss Of Dicer In Newborn Melanocytes Leads To Premature Hair Graying And Changes In Integrin Expression
Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
research The FRZB Gene Regulates Hair Follicle Development in Rabbits via the Wnt/β-Catenin Signaling Pathway
The FRZB gene slows hair growth in rabbits.
research Developing a Framework for Sources of New Product Ideas
The authors suggest systematically sourcing new product ideas from various internal and external places to improve innovation.
research Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies
Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
research Recent Approaches of Antibody Therapeutics in Androgenetic Alopecia
Antibody treatments show promise for hair loss but need more research.
research Engineered Exosomes Biopotentiated Hydrogel Promote Hair Follicle Growth via Reprogramming the Perifollicular Microenvironment
The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.
research Hypoxia Enhances the Hair Growth-Promoting Effects of Embryonic Stem Cell-Derived Mesenchymal Stem Cells Via NADPH Oxidase 4
Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.
research Hydrogel Crosslinking Modulates Macrophages, Fibroblasts, And Their Communication During Wound Healing
Softer hydrogels help wounds heal better with less scarring.
research Novel Janus Kinase Inhibitors in the Treatment of Dermatologic Conditions
JAK inhibitors show promise for treating various skin diseases.
research Ajuga Reptans L. Herb Extracts: Phytochemical Composition And Pharmacological Activity Screening
Ajuga reptans L. extracts have strong antioxidant, anti-inflammatory, liver-protective, antimicrobial, and wound-healing properties.
research Efficacy of Topical Minoxidil and Finasteride Association Compared to Monotherapy in Men With Androgenetic Alopecia: A Prospective, Randomized, Controlled, Assessor-Blinded, 3-Arm, Pilot Trial
Using both minoxidil and finasteride together is more effective for hair growth than using either one alone in men with hair loss.
research In Vitro Culture Methods of Skin Cells for Optimal Skin Reconstruction by Tissue Engineering
New methods for growing skin cells can improve skin grafts by building blood vessels within them.
research Attempted Construction of Minoxidil: Carboxylic Acid Cocrystals; 7 Salts and 1 Cocrystal Resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
research Evaluation of Metabolic and Hormonal Parameters in Women with PCOS Living in the Black Sea Region
Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.
research The Pathophysiology of Polycystic Ovary Syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Skin-Specific Transgenic Overexpression of Ovine β-Catenin in Mice
Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
research Toxicity Assessment of the Green Dunaliella Salina Microalgae
Dunaliella salina microalgae is safe to eat and may boost health.
research The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research Targeted Delivery of Zinc Pyrithione to Skin Epithelia
Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
research Significant Correction of Disease After Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia
Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.
research The Role of Autologous Micrografts Injection from Scalp Tissue in the Treatment of COVID-19 Associated Telogen Effluvium: Clinical and Trichoscopic Evaluation
Injecting scalp tissue micrografts is a safe and effective treatment for hair loss after COVID-19.
research Metabolic Study of Androsta-1,4,6-Triene-3,17-Dione in Horses Using Liquid Chromatography/High Resolution Mass Spectrometry
The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.