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This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.

This study found that dengue virus infection caused inflammation and cell death in human hair-follicle dermal papilla cells, which may contribute to increased hair shedding observed during the epidemic in Taiwan.

This study found that while isotretinoin lowered levels of female hormones in patients with severe acne, it did not significantly impact ovarian reserve function.

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by interacting with SIRT1 and PARP1, highlighting a potential mechanism for addressing aging-related diseases.

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.

This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.

This review discusses the role of fibroblast heterogeneity in kidney pathology, particularly their contribution to tertiary lymphoid tissue formation, and reports no new results.

This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

This review reported that tripeptides, such as GHK and KdPT, show promise in enhancing wound healing through multiple mechanisms, including promoting cell migration, collagen deposition, and angiogenesis, while offering antimicrobial and anti-inflammatory benefits for both acute and chronic wounds.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This review discusses dietary interventions as a modifiable factor in managing hidradenitis suppurativa and reports no new clinical results, emphasizing the need for informed lifestyle choices.

This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.

This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.

In this study, the researchers identified a PBX1-SIRT1-PARP1 axis that plays a crucial role in reducing senescence and apoptosis in hair follicle-derived mesenchymal stem cells.

This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.

This review discusses the role of dermal papilla cells in hair follicle morphogenesis and regeneration and reports no new results; the authors emphasize the importance of these cells in hair growth and pigmentation regulation.

This study suggests that sodium-glucose cotransporter-2 inhibitors, alone or with metformin or GLP1RA, may improve metabolic and hormonal parameters in women with polycystic ovary syndrome.

This review discusses the role of the mTORC1 pathway in acne pathogenesis in relation to diet and reports no new results.

This review discusses the potential of adipose-derived stem cells for regenerative medicine, highlighting their ability to differentiate, secrete factors, and modulate the immune response, but reports no new findings.

This study found that γδ T cells play a role in regulating stromal behavior, influencing the composition and vascularity of fibrotic tissues during the foreign body response.

This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.

This study found that treatment with a synthesized autophagy inducer improved skin barrier function and hair damage in dogs with atopic dermatitis or hyperadrenocorticism by reducing pro-inflammatory cytokines.

This study identified a group of dermal fibroblasts near hair follicle stem cells in mice that facilitate hair regeneration by creating a biomechanically compliant extracellular matrix, enhancing stem cell activation and promoting a positive feedback loop for tissue regeneration.

In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.

This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.

This review highlights that isotretinoin effectively treats acne by addressing its pathogenic mechanisms, although managing its teratogenic risk and side effects through structured monitoring is crucial for safe use.

This review discusses the heterogeneity of Tregs in normal and tumor environments, emphasizing the complexity of targeting tumor-resident Tregs while maintaining systemic immune tolerance, but reports no new findings.

This study suggests that metformin's ability to enhance insulin sensitivity may improve acanthosis nigricans by addressing the underlying insulin resistance.