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Sex hormones, especially androgens, play a key role in causing acne.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

SIRT7 protein is crucial for starting hair growth in mice.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

High mTORC1 activity slows hair growth and causes it to lose color.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Caffeine can damage hearing cells and affect hearing recovery after ear trauma.

Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.

Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Cannabinoids might help treat skin problems but more research is needed to be sure.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.