Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the complex role of Runx family genes in regulating stem cells in blood and skin tissues and reports no new experimental results.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.

This study found that hidradenitis suppurativa is associated with increased serum levels of hypoxia-inducible factor-1α, suggesting its role in the disease's pathogenesis and as a treatment target.

This review discusses the impact of sarcoptic mange on wombats and evaluates antiparasitic drugs like ivermectin, moxidectin, and fluralaner for treating the disease, but it presents no new clinical results.

This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.

This study found that lineage-restricted loss of p63 in murine thymic epithelial cells resulted in severe thymic hypoplasia and absence of hair follicles, indicating p63's critical role in thymic and hair follicle development.

This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.

This article describes how PESCADOR software assists in creating detailed biological pathway charts from PubMed abstracts, focusing on hair and breast development case studies without providing new clinical results.

This article reviews the classification and characteristics of water soluble vitamins, focusing on their varying solubility and functions, and reports no new experimental findings.

This systematic review of Mendelian randomization studies reports that autoimmune thyroid disease is associated with increased risk for numerous health conditions, including coronary atherosclerosis and rheumatoid arthritis, while decreasing risks for others, such as lung cancer.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This study identified peripheral myeloid cells as the earliest dysregulated immune cells in PINK1 KO mice with Parkinson’s-like symptoms following intestinal infections, suggesting that PINK1 regulates gut immune functions linked to early Parkinson’s disease mechanisms.

In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.

This review discusses the impact of calorie restriction on enhancing stem cell potency and regenerative abilities in mammalian tissues and reports no new experimental results.

This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.

This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

This study found that wire brush hair snares collected the most hair from Eurasian Lynx in controlled enclosures, suggesting potential for sampling genetic material from similar felid species.

This review discusses the nutritional and medicinal benefits of breadfruit and highlights challenges in promoting its consumption, but reports no new empirical findings.

This article discusses the highlights and key topics from the 17th Congress of the European Academy of Dermatology and Venereology but reports no new results.

This review highlights the role of disrupted glycolysis in exacerbating reproductive and metabolic abnormalities in PCOS and suggests that agents like metformin and resveratrol may help restore glycolytic balance and improve ovarian function.

This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.

This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.

This paper provides a comprehensive review of melanocytes' roles in skin biology, focusing on their pigmentation and immune functions, and suggests potential research opportunities for preventing and treating skin disorders.

This review examines studies from 2019-2022 on dietary treatments for skin diseases, highlighting various foods and supplements that may aid in managing conditions like acne, psoriasis, and alopecia areata.

In this study, the researchers identified a PBX1-SIRT1-PARP1 axis that plays a crucial role in reducing senescence and apoptosis in hair follicle-derived mesenchymal stem cells.

This study found that the circular RNA circCOL1A1 influences the formation of superior-quality brush hair in white goats by regulating hair follicle stem cell behavior and interacting with the miR-149-5p/CMTM3/AR axis.

This review discusses the scalp and follicular microbiome's potential role in hair diseases and the emerging interest in microbiome-targeted therapies, but reports no new clinical findings.

This study found that the purified compound VB1 from Vitex negundo seeds may reduce UVA-induced skin aging by targeting MAPK1 and demonstrated its potential in mice.