January 2018 in “International journal for pharmaceutical research scholars” In this study, topical application of tonic preparations containing 5% ethanol extract of Phyllanthus niruri to shaved mice showed potential as a hair growth enhancer, as indicated by observations of increased hair length and weight over a 21-day period.
January 2016 in “Mercer University Libraries (Mercer University)” This study found that an anhydrous gel formulation containing sertaconazole nitrate effectively penetrated the stratum corneum for treating fungal infections without causing irritation.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
July 2013 in “Pharmaceutical Regulatory Affairs Open Access” Formulation F1 is the best for delivering finasteride effectively.
This study reported that the HG3 formulation of a Ketoconazole anti-dandruff gel exhibited superior drug release and antifungal efficacy without causing skin irritation, compared to other formulations tested.
May 2004 in “International Journal of Cosmetic Science” This study suggests that selecting and controlling emollient systems can regulate the skin penetration of active ingredients in cosmetic formulations, impacting their efficacy.
81 citations
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February 2022 in “Bioactive Materials” This study reported the development of pH-responsive nanoparticles that effectively deliver vancomycin in a controlled manner, demonstrated enhanced antibacterial activity, and showed promise for clinical applications by targeting bacterial infection sites with programmable drug release.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.
26 citations
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July 2023 in “International Journal of Nanomedicine” The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.
24 citations
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January 2018 in “Journal of Pharmacy And Bioallied Sciences” This study found that a licorice-based herbal shampoo offered excellent cleansing ability and user satisfaction without microbial contamination, suggesting potential benefits for hair and scalp issues, but further studies are needed.
20 citations
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August 2023 in “Saudi Pharmaceutical Journal” This study found that cetirizine-loaded niosomal gels demonstrated superior skin deposition and retention compared to plain cetirizine gel, suggesting potential for improved topical management of alopecia.
20 citations
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April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences” This study investigated the use of methylene blue in a niosomal hydrogel for photodynamic treatment of acne and found that it led to significant improvement in inflammation compared to IPL treatment.
10 citations
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January 2013 in “International Journal of Research in Pharmaceutical Sciences” This study found that a microemulsion containing extracts of Hibiscus rosa sinensis and Murraya koenigii was non-irritating and more effective at controlling hair loss than a standard marketed formulation.
9 citations
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January 2010 This study reports that a 100% herbal hair dye composed primarily of Cymphomandra betacea, Tagetes erecta, and Aloe vera gel provides permanent hair color without causing hair damage, loss, or skin irritation compared to synthetic dyes.
6 citations
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January 2018 in “Research Journal of Topical and Cosmetic Sciences” In this study, researchers developed an herbal liquid shampoo using ingredients like shikekai and tulsi powder, aiming for safety and efficacy without the damaging effects of chemical alternatives, and found that it could clear dandruff and dirt while enhancing hair strength and growth.
5 citations
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August 2021 in “Journal of drug delivery and therapeutics” This study evaluated a herbal shampoo containing fermented rice water and traditional herbs, finding it safe and effective for reducing hair fall, with notable properties like good foam ability, cleansing action, and soothing qualities.
4 citations
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March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” The study formulated a hair application Ayurvedic herbal oil using various plant materials, including Neem and Amla, and reported that all evaluated parameters, such as specific gravity and irritation tests, were acceptable and within standard limits.
2 citations
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November 2021 in “International Journal of Applied Pharmaceutics” This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.
2 citations
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October 2021 in “International journal of pharmaceutical chemistry and analysis” This research developed a herbal shampoo powder using traditional plant ingredients and found it met ideal physicochemical standards, but further studies are needed to enhance its quality, performance, and safety.
2 citations
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August 2019 in “Journal of drug delivery and therapeutics” This study reports the formulation and evaluation of an herbal shampoo, "Herbello", aimed at improving antidandruff activity using various natural ingredients.
2 citations
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July 2018 in “Journal of drug delivery and therapeutics” In this study, researchers formulated an onion and eucalyptus oil herbal shampoo for dry hair, finding that the F2 batch provided better results in terms of cleansing, dandruff reduction, and microbial activity compared to other batches, with added benefits of nourishing hair and promoting growth.
1 citations
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December 2022 in “Research journal of topical and cosmetic sciences” This study evaluated a polyherbal shampoo containing natural ingredients and found it demonstrated good froth stability, cleansing ability, and conditioning activity, but called for further validation of its overall quality.
This study reported excellent results for hair growth with a newly formulated polyherbal hair oil using traditional herbs like Shikhakai powder and Neem leaves.
1 citations
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June 2018 in “Pharmaciana” In this study, researchers developed a hair tonic using 7.5% Aloe vera extract and 2.5% licorice extract, finding that the formula with 15% ethanol showed optimum activity by promoting hair growth and increased hair weight in rabbits over 28 days.
1 citations
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January 2018 in “International Journal of Pharmaceutical Sciences and Drug Research” This study describes the development of a minoxidil gel using the copolymer Sepineo P 600, showing improved spreadability, occlusivity, adhesiveness, and stability compared to minoxidil lotion, without causing skin corrosion, making it a potentially more effective treatment form for alopecia areata.
1 citations
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January 2016 in “Der pharmacia lettre” This study found that shampoo formulated with Eclipta alba extracts may promote hair growth and act as an antidandruff agent due to its antifungal activity against Malassezia.
1 citations
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June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the formulated polyherbal shampoo is a safe, stable, and effective natural alternative for routine hair care, offering good cleansing, conditioning, and protection without causing skin irritation.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study concluded that the formulated polyherbal shampoo using natural ingredients is safe, stable, and effective for hair care, showing good cleansing, conditioning, and nourishment properties as a natural alternative to synthetic shampoos.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” In this study, a new hair serum featuring Catharanthus roseus extract was formulated and evaluated, showing a stable and appealing product with potential hair growth-promoting properties, positioning it as a promising herbal alternative to synthetic agents like minoxidil.