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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Liposomes could improve how skin care products work but are costly and not very stable.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.

Advanced human skin models improve drug development and could replace animal testing.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Researchers found 15 new genetic links to skin traits in Japanese women.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Trichohyalin is also found in the outer layers of normal human skin.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Applying calreticulin can speed up wound healing in diabetics.

Mice without certain skin proteins had abnormal skin and hair development.

Fully regenerating human hair follicles not yet achieved.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.