75 citations,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
74 citations,
April 2005 in “Dermatologic Clinics” Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.
74 citations,
September 1980 in “Medical Clinics of North America” Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.
69 citations,
July 2015 in “Pharmacotherapy” Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
61 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.
61 citations,
October 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The document concludes that accurate diagnosis is crucial for effectively treating common scalp disorders, which often have similar symptoms.
59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
52 citations,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
48 citations,
November 1992 in “International Journal of Dermatology” Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
46 citations,
September 2016 in “Clinical, Cosmetic and Investigational Dermatology” Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
46 citations,
January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
44 citations,
April 2015 in “PubMed” Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
42 citations,
January 2006 in “Obstetrical & Gynecological Survey” The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
41 citations,
March 2007 in “Journal of dermatological science” Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
40 citations,
December 2016 in “Journal of Dermatological Treatment” JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
38 citations,
June 2004 in “Human Reproduction” The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
38 citations,
July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
37 citations,
February 2014 in “Journal of Dermatology” Valproic acid increases hair count in men with hair loss.
36 citations,
June 2019 in “eLife” The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
34 citations,
October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
34 citations,
May 2017 in “Lasers in Surgery and Medicine” Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.
34 citations,
September 1992 in “Journal of the American Academy of Dermatology” Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.
34 citations,
April 1973 in “The American journal of clinical nutrition” Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.
31 citations,
April 2018 in “Plastic and Reconstructive Surgery” PRP therapy may improve skin and hair conditions, but more research with standard methods is needed.
30 citations,
June 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
29 citations,
January 2014 in “Frontiers in physiology” Understanding and tracking our body's natural daily rhythms could help improve heart health.
29 citations,
January 1993 in “Dermatologic Clinics” Certain medications and maintaining adequate iron levels can help manage women's hair loss.
28 citations,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
28 citations,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
28 citations,
August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.