May 2022 in “Dermatology practical & conceptual” This study developed new graded visual scales integrating macroscopic and trichoscopic images for assessing the severity of androgenetic alopecia in men and women, potentially aiding in more objective disease evaluation.
23 citations
,
April 2006 in “Skin Research and Technology” This study observed that hair density and growth rates vary by location and age, and the presence of thin hairs predominates in younger women with mild patterned hair loss.
15 citations
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February 2003 in “British Journal of Dermatology” This study demonstrated that using morphometric and 3D reconstruction software to evaluate scalp biopsies in non-cicatricial alopecias may be feasible and sensitive for detecting subtle follicular changes.
102 citations
,
October 1996 in “Dermatologic Clinics” Photographic documentation crucial for evaluating hair growth in androgenetic alopecia.
23 citations
,
January 2008 in “Skin Pharmacology and Physiology” This study demonstrated that optical coherence tomography effectively detects significant changes in hair structure caused by steroid treatment, suggesting its potential use in doping control and clinical therapy monitoring.
December 2025 in “Y HOC TP HO CHI MINH” This study found that Trichoscope can effectively reveal clinical features of alopecia areata and androgenic alopecia, making it a useful tool for diagnosis and monitoring.
April 2024 in “Clinical dermatology review (Print)” In this study, trichoscopy was found to be an effective noninvasive tool for diagnosing female pattern hair loss at early stages, potentially eliminating the need for scalp biopsies.
20 citations
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April 2011 in “British Journal of Dermatology” Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
September 2015 in “Dermatologic Surgery” In this study, the researchers developed a computer-aided imaging system to quantitatively measure baldness in Chinese women with female pattern hair loss, potentially improving the precision of severity evaluation compared to traditional scales.
February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
9 citations
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September 2022 in “Frontiers in Physics” This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.
October 2022 in “International Journal of Research in Dermatology” This study suggests that hormonal disturbances play a role in female pattern hair loss and that trichoscopy may be a useful tool for diagnosis and differentiation from other conditions.
4 citations
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April 2001 in “Experimental Dermatology” This study used a novel HPLC-radiomatic flow scintillation system to measure 5α-reductase activity in dermal papillae from miniaturized hair follicles of the human occipital scalp, revealing significant variability in enzyme activity across samples.
5 citations
,
February 2015 in “Dermatologica Sinica” In this study, a computer-aided imaging system accurately measured the width of balding areas in female pattern hair loss, correlating strongly with clinical staging severity.
78 citations
,
August 2002 in “Experimental Dermatology” This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.
November 2021 in “International Journal of Trichology” This study found that trichoscopy can confirm the diagnosis and assess the clinical severity of female androgenetic alopecia, correlating specific features with different severity grades.
4 citations
,
February 2020 in “Journal of Cosmetic Dermatology” This study found that androgenetic alopecia was the most common cause of frontal hairline recession in Egyptian female patients, supporting the use of trichoscopy as a noninvasive diagnostic tool.
6 citations
,
June 2010 in “Dermatologica Sinica” In this study, researchers reported two cases of the rare and benign follicular tumor called panfolliculoma, highlighting its differentiation across all hair follicle components, which is distinct from similar conditions like trichofolliculoma.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
5 citations
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June 2024 in “Cureus” In a study involving adults with mild to moderate dandruff, researchers observed that post-hair wash interventions significantly reduced dandruff as measured by three assessment methods, showing substantial reliability and correlation, which supports their use in clinical settings for evaluating scalp dandruff treatments.
September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that high-speed optical coherence tomography may be a promising non-invasive tool for analyzing human hair conditions.
1 citations
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June 2022 in “Journal of The American Academy of Dermatology” Combining scalp photos with hair density and caliber measurements gives a more accurate assessment of hair loss.
1 citations
,
November 2014 in “Journal of Biomedical Optics” This study introduced a noninvasive spectroscopy method to assess hair follicle stages in mice by measuring skin diffuse reflectance and melanin dynamics, offering a potential tool for hair regeneration research.
In this hospital-based observational study involving 30 participants, researchers found no statistically significant difference in the force needed to pluck anagen versus telogen hair in the frontal and occipital scalp regions of women with female pattern hair loss.
January 2015 in “Dermatología Venezolana” This review details the use of trichoscopy for analyzing hair and scalp structures to differentiate between types of alopecia but does not report new clinical results.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed non-invasive methods to monitor hair shaft, melanin, and collagen dynamics in C57BL/6 mice across different hair follicle cycle phases, supporting non-invasive research in hair loss treatment development.
41 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.
15 citations
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March 2016 in “The American Journal of Dermatopathology” In this study, Demodex mites were infrequently found in scalp biopsies performed for hair loss, and most cases were nonpathogenic, but a minority showed folliculitis with a strong response to metronidazole therapy.
7 citations
,
April 1987 in “International Journal of Dermatology” This article reports no new clinical findings and provides no abstract, focusing on imipramine-induced lesions resembling alopecia areata.
2 citations
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May 2025 in “Infection” This source underscores the need for a multidisciplinary effort to raise awareness of Demodex and demodicosis, suggesting that prioritizing research, diagnostics, and treatment development could enhance global health outcomes and improve quality of life for affected individuals.