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Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Cetuximab can cause eyelash growth, which is rare but manageable.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.

Skin infections in cats are more common than thought, often affect young cats with allergies, and need better treatments.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.