research Trichodystrophies: A Hair-Raising Differential Diagnosis
The guide helps doctors diagnose hair problems by suggesting a thorough patient history, physical exams, and various diagnostic tools.
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research The Polycystic Ovary Syndrome: Challenges and Opportunities in Adolescent Medicine
Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
research Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia
This study explores a film-forming spray with 5% minoxidil for treating androgenetic alopecia, aiming to reduce side effects like dry scalp and irritation associated with traditional formulations. The spray forms a thin, non-sticky film that enhances drug contact time and permeability, leading to continuous release and improved patient comfort. The formulation was evaluated for pH, viscosity, spray angle, and drug content, with formulation F2 (1.8% hydroxypropyl methylcellulose E15) showing promising results. The study concludes that this novel delivery system could effectively treat patchy hair loss or baldness in men with androgenetic alopecia, improving therapeutic outcomes and patient compliance.
research Recent Approaches of Antibody Therapeutics in Androgenetic Alopecia
Antibody treatments show promise for hair loss but need more research.
research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
research A Randomized Controlled Study on the Safety and Efficacy of a Combination of 678nm Helmet-Type Low-Level Laser Therapy and Topical Minoxidil 5% in the Treatment of Male Androgenetic Alopecia
Using a laser helmet with Minoxidil works better for male hair loss than Minoxidil alone, with no extra side effects.
research Illuminating Microflora: Shedding Light on the Potential of Blue Light to Modulate the Cutaneous Microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research Novel Advances of Histone Modification in Inflammatory Skin Diseases and Related Treatment Methods
Histone modification is key in treating chronic inflammatory skin diseases.
research A Review on Polyherbal and Supplemental Approach to Treat Polycystic Ovarian Syndrome
Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).
research Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research Scarring Hair Follicle Destruction Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Advances in Mitochondria-Centered Mechanism Behind the Roles of Androgens and Androgen Receptor in the Regulation of Glucose and Lipid Metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Gynecological and Dermatological Aspects of Diagnostics of Polycystic Ovary Syndrome from Puberty to Menopause
PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Identification of an Osteopontin-Derived Peptide That Binds Neuropilin-1 and Activates Vascular Cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Hair Cortisol: A Biomarker of Chronic Stress in Animals and Its Association With Reproduction
High levels of cortisol in hair show long-term stress which can lower fertility in animals.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.
research Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes
Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
research Reimagining Hair Science: A New Approach to Classify Curly Hair Phenotypes via New Quantitative Geometrical and Structural Mechanical Parameters
A new system for classifying curly hair types using precise measurements can improve hair care products and cultural inclusion.
research The Multiple Uses of Azelaic Acid in Dermatology: Mechanism of Action, Preparations, and Potential Therapeutic Applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs
COX2 and ATP synthase control the size of hedgehog spines.
research Treatment of Indralupta Through Ayurveda: A Case Study
Ayurvedic treatment with local herbal applications successfully regrew hair in a patient with alopecia areata.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Hair Shaft Disorders: A Rare Case Series
The document concludes that proper diagnosis and treatment of hair shaft disorders require understanding their unique causes and avoiding hair-damaging practices.
research Serum Micronutrient Levels in Premature Canities: A Systematic Review and Meta-Analysis
Low levels of vitamin B12, ferritin, and calcium are linked to premature graying of hair.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin affects certain genes and pathways involved in cashmere goat hair growth.
research Clinical and Molecular Genetic Studies in Hereditary Hair Loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.