research Targeting to the Hair Follicles: Current Status and Potential
Hair follicles are promising targets for delivering drugs effectively.
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research Antisense Oligonucleotide Targeting Fibroblast Growth Factor Receptor-1 Stimulates Cellular Activity of Hair Follicles in an In Vitro Organ Culture System
Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
research Targeting Potential of Zinc Oxide Nanoparticles and Finasteride-Loaded Nano Lipidic Carriers-Infused Topical Gel - In Vitro and In Vivo Skin Permeation Studies
Nanocarriers in gel may reduce side effects of oral hair loss treatments.
research Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles
Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
research Squarticles as a Nanocarrier for Targeting Minoxidil to Hair Follicles and Dermal Papilla Cells
Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
research Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline
More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4
Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
research New Insights on Dandruff/Seborrhoeic Dermatitis: The Role of the Scalp Follicular Infundibulum in Effective Treatment Strategies
Effective dandruff treatment requires delivering antifungal agents to the scalp follicular infundibulum.
research Impairment of Autophagy May Be Associated with Follicular Miniaturization in Androgenetic Alopecia by Inducing Premature Catagen
Impaired autophagy may cause hair loss by triggering early catagen.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells
Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
research Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.
research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
research 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin
Only 40 nm nanoparticles can enter skin cells effectively for potential vaccine delivery.
research Hair Removal Using an Nd:YAG Laser System
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Novel Micelle Formulations to Increase Cutaneous Bioavailability of Azole Antifungals
New micelle solutions greatly improve skin delivery of certain antifungal drugs.
research Hidradenitis Suppurativa: A Review of Cause and Treatment
Hidradenitis suppurativa is a skin condition possibly caused by hair follicle issues, with treatments focusing on infection and inflammation.
research Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles
Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
research From Surgery to Pharmacology to Gene Therapy: The Evolution of Hair Restoration Techniques
Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.
research Vascular Mechanisms in Laser Hair Removal
Laser hair removal might also work by damaging blood vessels around hair follicles.
research Recent Developments in Alopecias
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Report of a Patient with Acne Conglobata and Perifolliculitis Capitis Abscedens et Suffodiens
A patient with a rare scalp condition showed improvement with isotretinoin and other medications.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
research Nanocrystal Structure of Minoxidil: A Safe Stimulator for Hair Growth in C57BL/6 Mice
Minoxidil nanocrystals improved hair growth in mice more effectively and safely than regular Minoxidil.
research Integrating Technology in Facial Plastic Surgery
Surgeons should evaluate new technologies critically, offer a range of services including non-surgical options, and be aware of marketing influences to meet patient needs and maintain a successful practice.