research A Comparison of Reticle Size to Determine Follicular Unit Density in Hair Restoration
This article discusses various affiliations of the authors with no reference to new research findings.
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research Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline
In this study, researchers found that the number of dermal papilla cells in hair follicles determines hair size and shape in mice, suggesting potential avenues for addressing hair loss.
research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument
In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.
research The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration
In this study, curcumin-loaded nanoparticles with a size of 400 nm showed optimal accumulation in human hair follicles after seven days, although mouse models differed significantly in penetration and retention, indicating limitations in their suitability for follicular drug delivery studies.
research Selective follicular targeting by modification of the particle sizes
This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.
research Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting
The study found that cyproterone acetate-loaded nanostructured lipid carriers, particularly those with a 300 nm diameter, improved skin penetration and targeted hair follicles more effectively than free cyproterone acetate.
research ASSESSMENT OF HEALTH RELATED QUALITY OF LIFE IN POLY CYSTIC OVARIAN SYNDROME PATIENTS AND FACTORS AFFECTING OVARIAN FOLLICULAR SIZE
This study found that metformin improved quality of life for overweight and obese women with PCOS, while clomiphene citrate and inositol were more effective for non-obese and underweight women.
research Use of beard hair as a donor source to camouflage the linear scars of follicular unit hair transplant
This article discusses various methods for minimizing and repairing strip scars from follicular unit hair transplants but reports no new clinical results.
research Follicular delivery of a novel peptide therapeutic for the treatment of androgenic alopecia
In this study, a novel liposomal peptide formulation significantly enhanced hair growth in mice compared to minoxidil, but results on human tissue penetration were inconclusive, suggesting further research is needed for translation to human use.
research An Analysis of Follicular Punches, Mechanics, and Dynamics in Follicular Unit Extraction
This article reviews factors affecting follicular unit extraction, emphasizing the need to tailor procedures to individual patient characteristics, but reports no new experimental findings.
research Variations of Hair Follicle Size and Distribution in Different Body Sites
This study found that hair follicle characteristics vary significantly across different body sites, with the forehead and calf showing the highest potential follicular reservoirs, challenging previous assumptions about skin appendage distribution.
research Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients
In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
research Multi-Modal Imaging to Assess the Follicular Delivery of Zinc Pyrithione
This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.
research Biology of Hair Growth
Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
research Development and Evaluation of Herbal Formulations for Hair Growth
This study found that a herbal hair oil containing 7.5% concentrations of specific plant extracts showed effective hair growth activity comparable to 2% minoxidil, with particularly promising results from oils prepared using the cloth pouch decoction method.
research Preparation, evaluation and hair growth stimulating activity of herbal hair oil.
This study found that a herbal hair oil formulation with 7.5% concentration of each active ingredient, prepared using the boiling method, showed excellent hair growth activity comparable to 2% minoxidil.
research Primary scalp alopecia: new histopathological tools, new concepts and a practical guide to diagnosis
This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
research Concomitant Effect Of Present Herbal Formulation With Marketed Allopathic Formulation For The Evaluation Of Hair Growth
This study investigated a herbal extract combining Emblica officinalis with 2% minoxidil solution for hair growth and found it significantly enhanced follicular size and prolonged hair growth phases, suggesting it may be an effective hair growth treatment compared to standard minoxidil solutions.
research BH15 Nonsyndromic hypotrichosis: a rare case of congenital hypotrichosis 15 and management with minoxidil
This case report describes a rare genetic mutation causing congenital hypotrichosis, where a 2-year-old girl showed some improvement in hair growth with topical minoxidil treatment, supporting its potential use for this condition.
research Injectable Minoxidil for Hair Loss Disorders: A Systematic Review
This article highlights the need for a comprehensive review of injectable minoxidil for hair loss, as existing treatments primarily focus on topical and oral forms of the medication.
research Formulation and Evaluation of Polyherbal Lotus Oil
This study found that a herbal hair oil with 7.5% concentration of amla, hibiscus, bhringraj, and methi showed potent hair growth activity comparable to 2% minoxidil solution.
research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research A new practical classification for spatial distribution and morphology of human hair: Ahmad's LGMA classification
This study presents a new classification of adult human scalp hair patterns based on high-resolution photographs, which may assist hair restoration surgeons and dermatologists in determining appropriate punch size for follicular unit extraction.
research The Physicochemical, Biopharmaceutical, and In Vitro Efficacy Properties of Freeze-Dried Dexamethasone-Loaded Lipomers
This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.
research Scalp imaging techniques
This review discusses the role of scalp imaging techniques in trichology for researching drug delivery and toxicology, without presenting new clinical results.
research Developing formulations for drug follicular targeting: Nanoemulsions loaded with minoxidil and clove oil
This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.
research Investigation of differences in follicular penetration of particle-and nonparticle-containing emulsions by laser scanning microscopy
In this study, particles similar in size to keratin cells were surprisingly found to penetrate more efficiently into hair follicles due to a possible pumping effect from moving hairs.
research Minimizing injury to the donor area in follicular unit extraction (FUE) harvesting
This study found that intradermal injection of normal saline before follicular unit extraction significantly reduced wound size and skin mass removed compared to acute extraction, suggesting it minimizes skin injury in this procedure.
research Follicular Delivery of Nanocarriers to Improve Skin Disease Treatment
This study reports that optimal follicular penetration in nanocarrier-assisted drug delivery for skin diseases occurs with carrier sizes between 300 and 650 nm, while certain traditional medicine practices have shown effectiveness in treating skin conditions.
research Follicular Density and Ratios in Scarring and Nonscarring Alopecia
This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.