30 citations
,
May 2014 in “American Journal of Clinical Dermatology” This review discusses follicular and scarring disorders in skin of color and highlights the need for patient education and tailored therapeutic strategies, but does not report new clinical findings.
29 citations
,
July 2008 in “Journal of Cutaneous Pathology” This study found that follicular streamers are mostly present in non-scarring alopecia cases, and tracking their location can improve diagnosis accuracy.
3 citations
,
June 2020 in “Dermatologic Surgery” This study found that dense-packing megasession follicular unit extraction is a safe and effective method for treating extensive scarring alopecia, with a graft survival rate of 85% and high patient satisfaction.
56 citations
,
September 2010 in “Veterinary pathology” This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.
19 citations
,
February 2013 in “The American Journal of Dermatopathology” This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.
4 citations
,
January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
October 2024 in “Journal of Pakistan Association of Dermatologists” In this cross-sectional study, both follicular lichen planus and discoid lupus erythematosus were identified as common causes of scarring alopecia, affecting young people with a more favorable prognosis for hair regrowth in discoid lupus erythematosus compared to follicular lichen planus.
June 2024 in “Дерматовенерология Косметология” In this study, treatment with autologous follicular stem cells improved hair conditions in 57% of patients with androgenic and telogen effluvium alopecia, as confirmed by phototrichograms, indicating its potential effectiveness for non-scarring alopecia.
August 2018 in “Analysis of the application of various variants of bone plasty in victims with intraarticular fractures (Transplantology)” In this study, follicular microautotransplantation was found to be an effective outpatient surgical treatment for scarring alopecia, with transplanted follicles showing an average engraftment rate of 93.8% and providing a good cosmetic outcome that improves patients' quality of life.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.
179 citations
,
June 2000 in “The American journal of pathology” This study reports that the asebia-2J mutation in mice affects sebaceous gland function and leads to hair follicle destruction, offering a model for human scarring alopecias.
April 1906 in “The American Journal of the Medical Sciences” Keratosis Pilaris Atrophicans causes skin scarring and might be treated with a new synthetic retinoid.
41 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the benefits, techniques, and unique considerations of follicular unit extraction for hair grafting, but reports no new clinical results.
37 citations
,
June 2011 in “Journal of The American Academy of Dermatology” This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.
36 citations
,
January 2000 in “British journal of dermatology/British journal of dermatology, Supplement” This case study reports on a mother and daughter with ichthyosis follicularis, alopecia, and photophobia, noting consistent keratotic eruptions during the mother's pregnancies that improved postpartum.
22 citations
,
January 2017 in “Skin appendage disorders” This research analyzed 72 primary scarring alopecia cases in a Barcelona hospital, finding that the majority involved women, with a lymphocytic infiltrate and subacute onset in many cases, leading to stable disease, while neutrophilic cases had more acute episodes.
14 citations
,
December 2013 in “Anais Brasileiros De Dermatologia” This case report describes a young Brazilian woman with scalp psoriasis that progressed to the rare complication of scarring alopecia.
11 citations
,
August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
6 citations
,
May 2013 in “Dermatologic Surgery” FUE can be successfully done on African-American hair by using larger punch tools and careful techniques to reduce hair damage.
1 citations
,
December 2016 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This study reported that 80% of patients with non-scarring alopecia showed a clinical cure after treatment with unactivated platelet leukocyte autoplasma.
April 2026 in “Skin Appendage Disorders” This narrative review suggests that exosome-based therapy shows promise for hair regeneration, offering improvements in hair density and thickness with favorable short-term safety in early clinical studies.
January 2026 in “Journal of advanced Biomedical and Pharmaceutical Sciences” This review highlights niosomal cetirizine as a promising strategy for managing alopecia, potentially enhancing local bioavailability and reducing systemic exposure.
This study evaluated the therapeutic response of an Afro-descendant patient with non-scarring alopecia after prolonged use of alkaline straighteners and mechanical traction, highlighting the susceptibility of Afro hair to chemical and mechanical damage due to its structure.
This study examined molecular predictors of ritlecitinib efficacy in treating alopecia areata, highlighting the role of JAK3-dependent inflammation and follicular integrity as important factors in understanding disease mechanisms and potential therapeutic effectiveness.
February 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that ultraviolet-induced fluorescence dermoscopy enhanced the identification of follicular openings in alopecia areata, potentially aiding in the assessment of disease severity and treatment strategies.
August 2024 in “EMJ Dermatology” This review addresses the causes, mechanisms, and treatment options for the most common non-scarring alopecias in females, including telogen effluvium, alopecia areata, and female pattern hair loss.
November 2023 in “Facial Plastic Surgery” This study discusses the advantages and disadvantages of two hair graft harvesting methods, strip follicular unit transplantation and follicular unit excision, highlighting their implications for creating effective surgical plans for hair restoration without providing specific new results.
June 2023 in “JAAD case reports” This case report describes a 39-year-old female with cutis verticis gyrata and cicatricial alopecia, emphasizing the need for further understanding of the potential genetic associations and underlying mechanisms.
October 2022 in “Hair Transplantation” This chapter reviews causes of poor scarring in hair restoration procedures and discusses methods for improving donor site scars, reporting no new clinical results.
August 2017 in “Journal of evolution of medical and dental sciences” In this study, researchers evaluated trichoscopy in diagnosing non-scarring alopecia and found diagnostic value in observing diverse hair diameters in androgenetic alopecia, black dots and broken hairs in alopecia areata, and empty follicles in telogen effluvium, supporting trichoscopy's utility in differentiating alopecia types.