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The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

EGF makes hair follicles grow longer but stops hair production.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Skin fat helps with body temperature control and has other active roles in health.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The HR protein's role as a repressor is essential for controlling hair growth.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Androgens slow hair growth by altering Wnt signaling in balding cells.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Human hair follicles can make and process prostaglandins, which may affect hair growth.