August 2014 in “Plastic Surgery” Dr. WP Unger suggested that traditional strip harvesting might be better for hair transplants than Follicular Unit Extraction due to higher hair survival rates and less risk of a patchy look at the donor site.
July 2014 in “Plastic and Reconstructive Surgery” Hair follicles stored in a special medium had the highest survival rate, and "plucked" follicles and follicular units showed better growth after transplant.
19 citations,
July 2009 in “Clinical and Experimental Dermatology” The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
251 citations,
October 2006 in “Plastic and reconstructive surgery/PSEF CD journals” Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
162 citations,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
126 citations,
April 2006 in “International Journal of Dermatology” The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
124 citations,
July 1997 in “Journal of Biological Chemistry” Overexpressing a specific enzyme in mice causes hair loss and female infertility.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
109 citations,
March 2011 in “Journal of controlled release” New micelle solutions greatly improve skin delivery of certain antifungal drugs.
97 citations,
January 2020 in “Advances in chronic kidney disease” Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
97 citations,
September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
82 citations,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
56 citations,
July 2005 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections gives a better diagnosis of alopecia than using one method alone.
51 citations,
February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
43 citations,
October 2003 in “Journal of The American Academy of Dermatology” Hair transplanting is a useful, often overlooked treatment for female pattern hair loss.
42 citations,
October 2012 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
39 citations,
October 2010 in “Journal of The American Academy of Dermatology” Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.
38 citations,
August 2005 in “Veterinary dermatology” A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.
34 citations,
January 2018 in “International Journal of Dermatology” Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
31 citations,
November 2013 in “Dermatologic Clinics” The ARTAS robotic system for hair restoration is efficient with fewer cuts than manual methods, but it's limited to certain hair types and can still leave scars.
31 citations,
January 2012 in “Skin Research and Technology” The w/o lotion with blended cellulose improved curcumin skin penetration best.
28 citations,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
28 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Body and beard hair can be used for hair restoration in severely bald patients, but the technique is complex and costly.
27 citations,
January 2002 in “Exogenous Dermatology” Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.
24 citations,
December 2014 in “International Journal of Molecular Medicine” Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.
20 citations,
September 2018 in “Journal of cutaneous pathology” Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.
20 citations,
May 1992 in “The Journal of Dermatologic Surgery and Oncology” Dr. Norwood's analysis highlights the need for careful patient selection and strategic hair transplant design to create a natural-looking hair density.
19 citations,
February 2016 in “Journal of The American Academy of Dermatology” CD3+ T-cell presence is a reliable marker to tell apart alopecia areata from pattern hair loss.