December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this preprint, an integrative regenerative protocol involving microneedling, plant-derived exosomes, and other therapies was used to treat androgenetic alopecia in an elderly woman, resulting in improved hair density and scalp coverage.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This preprint reports meaningful improvements in hair density and scalp coverage in an elderly female with androgenetic alopecia treated through an integrative regenerative protocol, involving microneedling and plant-derived exosomes, among other non-pharmacological interventions focusing on cellular senescence pathways.
November 2025 in “Journal of Investigative Dermatology” Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
October 2025 in “Annals of Medicine and Surgery” This study discusses the potential of topical retinoids, vitamin A derivatives, to improve treatment outcomes for androgenetic alopecia by promoting hair growth through extending the anagen phase and stimulating follicular activity, offering a promising approach when combined with existing therapies.
August 2025 in “Journal of Investigative Dermatology” Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.
June 2025 in “Medical & Clinical Case Reports Journal” This systematic review concludes that exosomes may offer significant therapeutic potential for treating androgenetic alopecia, with observed improvements in hair density and follicular health, but further long-term clinical studies are necessary for validation.
May 2025 in “Frontiers in Bioengineering and Biotechnology” In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.
April 2025 in “Cytotherapy” In this case report, a 38-year-old male with androgenetic alopecia showed increased hair density and reduced follicular miniaturization after receiving UC-MSCs derived secretome injections, suggesting potential effectiveness and safety for hair restoration; further research is needed for broader validation.
October 2023 in “Journal of Pakistan Association of Dermatologists” In this study, reflectance confocal microscopy was shown to provide early insights into sub-clinical treatment progress in patients with androgenetic alopecia, potentially offering advantages over global photography.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential benefits of using topical caffeine products for treating androgenic alopecia but reports no new clinical findings; the authors highlight caffeine's possible positive effects based on existing studies.
This case report and literature review concluded that using the follicular unit extraction technique for hair transplants in androgenetic alopecia patients yields satisfactory aesthetic results and high patient satisfaction over 12 months.
March 2021 in “Uludağ Üniversitesi Tıp Fakültesi dergisi” This review discusses current treatment methods for managing androgenetic alopecia in men and women, but reports no new clinical results, highlighting the lack of a standard treatment guide.
This article discusses disruptions in hair cycle dynamics and follicular miniaturization associated with patterned hair loss, emphasizing androgen-related changes, and reports no clinical findings.
January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
January 2015 in “Faculty of 1000 Research Ltd” Androgenetic alopecia may be irreversible due to the detachment of a muscle from hair follicles.
April 2022 in “Journal of Investigative Dermatology” This paper presents an interactive quiz related to a study by Deng et al. (2022) in the Journal of Investigative Dermatology, examining androgen receptor-mediated paracrine signaling in androgenetic alopecia, but it provides no new clinical findings.
September 2021 in “CRC Press eBooks” This review discusses the diagnostic features of androgenetic alopecia through trichoscopy and reports no clinical results; it emphasizes hair shaft variability and yellow dots as key indicators.
October 2017 in “Journal of The European Academy of Dermatology and Venereology” Stem cells preservation in AGA could be a potential therapy, but more cases needed.
January 2007 in “Revista del Centro Dermatológico Pascua” This review discusses female androgenic alopecia, highlighting its potential difference from male androgenic alopecia and notes increased incidence, but reports no new clinical findings.
This review discusses male androgenetic alopecia treatments, noting that topical minoxidil and oral finasteride are FDA-approved and require continuous use to maintain hair retention effects, but reports no new clinical results.
14 citations
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January 2013 in “Journal of Cutaneous Medicine and Surgery” This study describes permanent scalp alopecia in patients receiving chemotherapy, radiation, or both, and highlights the need for further research to identify causative factors and mitigation strategies.
12 citations
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November 2014 in “PLOS Computational Biology” In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.
July 2026 in “Editora Pasteur eBooks” This narrative review explores current understanding and management of female pattern hair loss, highlighting the role of genetic and environmental factors, and discussing diagnostic approaches like trichoscopy alongside emerging therapeutic strategies.
September 2025 in “Biomolecules” This review analyzed the complex interactions within the skin microenvironment that influence hair follicle development and regeneration, exploring its role in hair-related disease treatment and highlighting research challenges and future directions.
January 2020 in “Revista Dermatológica Centro Uraga” This article describes how recognizing distinct trichoscopic features aids in diagnosing various dermatological conditions and hair loss, but it reports no new clinical findings.
East and Southeast Asians typically have less dense but thicker, straight black hair.
August 2021 in “Journal of The American Academy of Dermatology” This article discusses the androgenicity of progestins used in hormonal contraceptives and its potential impact on female pattern hair loss, but reports no new clinical findings.
16 citations
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May 2013 in “Australasian Journal of Dermatology” In this study, detailed examinations of alopecic lesions in two female Cronkhite-Canada syndrome patients suggested hair regrowth might occur without systemic corticosteroids if not required for gastrointestinal treatment, and hair loss may begin with anagen-telogen transition.
42 citations
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June 2009 in “Journal of Cosmetic Dermatology” In this study, researchers observed that follicular microinflammation significantly contributes to the early stages of male androgenetic alopecia, potentially leading to perifollicular fibrosis and follicle destruction as the condition progresses.
8 citations
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August 2014 in “Clinical and Experimental Dermatology” This study found that chronic telogen effluvium is a distinct condition from female pattern hair loss, with different pathogenic mechanisms observed in histomorphometric analyses.