January 2014 in “Pathology” RET mutation is important in familial medullary thyroid carcinoma, and BRAF mutation in papillary thyroid carcinoma is linked to more aggressive cancer and higher death rates.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
107 citations,
December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
102 citations,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
62 citations,
January 2003 in “Dermatology” Sunlight worsens hair loss; protect scalp.
47 citations,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
43 citations,
May 2011 in “Dermatologic Therapy” Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
43 citations,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
40 citations,
December 2011 in “British Journal of Dermatology” Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
33 citations,
September 2012 in “Australasian Journal of Dermatology” Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.
32 citations,
July 2011 in “Facial Plastic Surgery” New hair transplant methods offer more natural results and better graft survival, with ongoing research to increase donor hair options.
31 citations,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
31 citations,
November 2013 in “Dermatologic Clinics” The ARTAS robotic system for hair restoration is efficient with fewer cuts than manual methods, but it's limited to certain hair types and can still leave scars.
28 citations,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
27 citations,
January 2002 in “Exogenous Dermatology” Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.
23 citations,
May 2017 in “Journal of the American Academy of Dermatology” FFA patients have fewer melanocytes and thinner skin compared to others.
23 citations,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
21 citations,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
20 citations,
July 2006 in “Veterinary dermatology” Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.
19 citations,
May 1992 in “International Journal of Dermatology” Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.
13 citations,
October 2002 in “Journal of Investigative Dermatology” The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
12 citations,
January 2010 in “Hair transplant forum international” The survival rates of hair grafts are similar regardless of how they are trimmed.
12 citations,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
11 citations,
March 2008 in “Experimental Dermatology” A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
9 citations,
November 2017 in “Journal of Glaucoma” Latanoprost eye drops may cause skin depigmentation.
9 citations,
June 2008 in “Springer eBooks” Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.