2 citations
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January 2020 in “American Journal of Clinical Research and Reviews” This study suggests that hair follicles may be the primary target in the onset of various skin diseases, potentially spreading to affect the surrounding epidermis.
April 1906 in “The American Journal of the Medical Sciences” Keratosis Pilaris Atrophicans causes skin scarring and might be treated with a new synthetic retinoid.
1 citations
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November 2003 in “Annals of saudi medicine/Annals of Saudi medicine” This case report documents the first known instance of erythromelanosis follicularis faciei in a Saudi male, detailing its clinical and histopathological characteristics.
1 citations
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March 2013 in “Journal of Dermatological Case Reports” This case report describes an atypical presentation of lichen planopilaris affecting only facial vellus hair, without scalp involvement, in a 46-year-old man.
31 citations
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January 2014 in “International Journal of Trichology” This review summarizes the anatomy and physiology of the arrector pili muscle and discusses its potential role in hair loss disorders, reporting no new clinical results.
37 citations
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June 2011 in “Journal of The American Academy of Dermatology” This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.
10 citations
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May 2020 in “Dermatology Research and Practice” This review discusses "follicular hypoglycania" as a potential pathology in hair growth disorders and reports that proteoglycan replacement therapy may improve hair loss treatments, though it presents no new clinical trial results.
78 citations
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April 1994 in “Archives of dermatology” This study suggests genetic and clinical heterogeneity in keratosis pilaris atrophicans, with variations in inheritance patterns, severity, and response to treatment among 21 individuals observed.
9 citations
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February 2001 in “Journal of Dermatological Science” This study found that the expressions of CDK inhibitors p21waf1/cip1 and p27kip1 were higher during the anagen phase compared to telogen, suggesting a role in follicular epithelial cell differentiation.
August 2024 in “Indian Dermatology Online Journal” In this retrospective study, researchers described the dermoscopic features of dermatitis cruris pustulosa et atrophicans in 30 patients, finding that follicular-based pustules and other specific features were predominant, with male patients being more affected and primarily involving the lower extremities.
January 2005 in “Journal of Cutaneous Pathology” This article discusses various disorders of the hair erector muscle, compiling conditions that involve it passively or actively, but reports no new clinical findings.
71 citations
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March 1995 in “Journal of The American Academy of Dermatology” This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.
39 citations
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October 2010 in “Journal of The American Academy of Dermatology” This study reported that alopecia occurred in 2.5% of patients with mycosis fungoides or Sézary syndrome, with some cases resembling alopecia areata and others associated with specific skin lesions.
7 citations
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August 2018 in “The American Journal of Dermatopathology” This study describes a newly observed "inflammatory vellus involvement" pattern in early frontal fibrosing alopecia, which may lead to misdiagnosis due to the absence of typical histological features.
December 2024 in “Skin Appendage Disorders” This case report highlights the diagnostic challenges of distinguishing folliculotropic mycosis fungoides from alopecia areata and lichen planopilaris, emphasizing the importance of histopathological evaluation for accurate diagnosis and treatment.
15 citations
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February 2006 in “Journal of Investigative Dermatology” More research is needed to understand and treat cicatricial alopecias.
December 2022 in “Research Square (Research Square)” In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.
October 2022 in “Research Square (Research Square)” This study found that type I interferon response-related genes activated by RIG-1 and IL-17 pathways were significantly up-regulated in hair follicle and skin samples with chronic discoidal lupus erythematosus.
158 citations
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February 2000 in “Archives of dermatology” This study reports that some patients with androgenetic alopecia may also exhibit clinical and histological features of inflammation and fibrosis, similar to those found in lichen planopilaris.
46 citations
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November 2022 in “The Journal of Dermatology” This review discusses recent findings on the mechanisms driving bullous pemphigoid, highlighting epitope spreading and the roles of regulatory T cells, and reports no new experimental results.
18 citations
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June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
14 citations
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March 2019 in “Facial Plastic Surgery Clinics of North America” This review discusses hair restoration procedures for transgender patients undergoing gender transformation surgery and describes the authors' surgical approach but reports no clinical outcomes.
11 citations
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May 2024 in “Reproductive Biology and Endocrinology” In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.
9 citations
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January 2020 in “Postepy Dermatologii I Alergologii” This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.
8 citations
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June 1934 in “Archives of Dermatology and Syphilology” This review discusses cases of ringworm of the scalp, highlighting the potential for spontaneous cure when the infection is caused by an organism pathogenic to animals, and reports no new clinical results.
7 citations
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March 2017 in “Medical Hypotheses” This study suggests that dysfunctions and altered expression of aquaporins may play a role in PCOS-related disorders, potentially impacting folliculogenesis and integrating with the insulin-dependent hypothesis of PCOS pathogenesis.
1 citations
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September 2023 in “International Journal of Dermatology” In this study conducted at a tertiary dermatological clinic, researchers identified and described the clinical, dermoscopic, and histopathological features of preclinical folliculitis keloidalis, including novel dermoscopic findings such as perifollicular scale, which was associated with fibrosis.
1 citations
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June 2006 in “Experimental dermatology” This article reviews possible pathogenesis scenarios for hidradenitis suppurativa and emphasizes the need for focused research on the innate immune system of hair follicles to better understand the disease.
In this study, researchers used an integrated in silico approach to demonstrate that Polygonum multiflorum combats androgenetic alopecia via anthraquinone emodin, which targets PI3K catalytic subunits differently from traditional antiandrogenic treatments, showing potential as a novel therapeutic strategy.
September 2025 in “Journal of Investigative Dermatology” This research found that deleting the SLC3A2 gene in hair follicle stem cells disrupts their maintenance and proper differentiation, leading to hair follicle growth defects and altered skin regeneration through a YAP/Taz-dependent pathway.