69 citations,
December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
25 citations,
June 2015 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
18 citations,
October 2002 in “Veterinary dermatology” Five Weimaraners had a milder form of color dilution alopecia causing hair loss and skin issues.
12 citations,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
11 citations,
August 2017 in “American Journal of Dermatopathology” EVG staining helps tell apart follicular scars from follicular streamers, aiding in diagnosing different types of hair loss.
9 citations,
June 2003 in “Veterinary dermatology” Boxer dogs may have a genetic skin condition that worsens seasonally and can be treated with certain medications.
2 citations,
June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
263 citations,
February 2011 in “Journal of Controlled Release” Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
9 citations,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
8 citations,
July 2014 in “Anais Brasileiros de Dermatologia” A man's scalp condition was misidentified as hair loss dots but was actually a common follicular disorder.
9 citations,
January 2014 in “World journal of clinical cases” Neomycin is a common cause of follicular contact dermatitis, which is treated by avoiding the allergen and using creams.
1 citations,
July 2023 in “Cosmetics” The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
1010 citations,
August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
6 citations,
May 2022 in “Pharmaceutics” Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.
16 citations,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
November 2009 in “Reactions Weekly” Two women lost hair after mesotherapy for hair loss, with one having permanent and the other temporary hair loss.
3 citations,
January 2016 in “Skin appendage disorders” Possible causes of female hair loss include androgenetic alopecia, telogen effluvium, cicatricial alopecia, and alopecia areata incognita; diagnosis and treatment require dermoscopy and histopathology.
3 citations,
April 2010 in “The American Journal of Dermatopathology” Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
1 citations,
January 2019 in “Acta dermato-venereologica” The woman's skin and hair symptoms were confirmed as frontal fibrosing alopecia, and while facial papules are common in such cases, there's no effective local treatment, but systemic treatments can help.
1 citations,
January 2020 in “Skin appendage disorders” Hair transplants for male baldness can show inflammation and fibrosis, but more research is needed to confirm LPP presence.
October 2023 in “Research Review” Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.
January 2018 in “Skin appendage disorders” A woman's hair loss was correctly diagnosed as Lichen planopilaris after initial misdiagnosis, highlighting the usefulness of trichoscopy in diagnosing hair disorders.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
158 citations,
February 2000 in “Archives of dermatology” Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
130 citations,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
126 citations,
April 2006 in “International Journal of Dermatology” The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
112 citations,
July 2008 in “Dermatologic Therapy” Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
90 citations,
July 2008 in “Dermatologic therapy” Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
research Acne
58 citations,
January 1997 in “Dermatologic Clinics” Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.