69 citations,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
64 citations,
April 2005 in “Journal of Investigative Dermatology” Topical oligonucleotide therapy targets hair follicles effectively.
57 citations,
June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
55 citations,
January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
54 citations,
November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
53 citations,
May 2010 in “Dermatologic Surgery” Hair transplantation may not work for Frontal Fibrosing Alopecia as transplanted hair was lost when the disease came back.
51 citations,
December 2003 in “The FASEB Journal” The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.
51 citations,
May 1984 in “Journal of the American Academy of Dermatology” Benign follicular mucinosis involves immune cells attacking hair follicles.
49 citations,
August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
48 citations,
April 1995 in “PubMed” Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.
47 citations,
September 2008 in “British Journal of Dermatology” Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
43 citations,
January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
41 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.
40 citations,
March 2019 in “Pharmaceutical development and technology” Smaller particles of the drug carrier penetrated skin better, with 300 nm size being best for targeting hair follicles.
40 citations,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
40 citations,
June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
39 citations,
January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.
35 citations,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
35 citations,
June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
35 citations,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
35 citations,
November 2010 in “Journal of Cutaneous Pathology” Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
34 citations,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
33 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
33 citations,
September 1998 in “Dermatologic Surgery” Surgeons suggested a standard system for hair transplant methods to improve communication and results.
32 citations,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
32 citations,
August 1982 in “Journal of the American Academy of Dermatology” GLPLS and LPP are variants of lichen planus.
31 citations,
September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
31 citations,
September 1996 in “Differentiation” The upper dermal sheath can regenerate hair in rats.
29 citations,
July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.