11 citations,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
9 citations,
January 2013 in “BioMed research international” The conclusion suggests a new acne treatment that controls bacteria by reducing water in the skin's pores using sugar-like substances.
November 2018 in “Journal of investigative dermatology, venereology and cosmetology” Biofield Energy Treatment, specifically The Trivedi Effect®, can potentially enhance hair growth by increasing the growth activity of human dermal papilla cells.
194 citations,
March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
February 2024 in “Drug Delivery and Translational Research” A new liposomal formulation improves drug delivery and hair growth for treating hair loss without causing skin irritation.
9 citations,
January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
39 citations,
April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
521 citations,
January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
April 2022 in “Journal of Investigative Dermatology” Androgenetic alopecia causes hair thinning due to increased androgen activity, treatable with minoxidil and finasteride.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
1 citations,
March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
January 2014 in “Hair transplant forum international” Hair follicle cloning is possible but faces many challenges before it can replace traditional hair transplants.
29 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
10 citations,
September 2021 in “International Journal of Nanomedicine” Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
7 citations,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
122 citations,
April 2020 in “American Journal Of Pathology” The document reviewed the pathobiology of skin aging, identifying it as a degenerative process influenced by intrinsic and environmental factors, leading to structural changes such as epidermal thinning, loss of dermal papillae, and decreased collagen and elastin, which contribute to wrinkles and sagging. It highlighted the role of stem cell dysfunction, genetic factors, and immune system decline in skin deterioration, noting increased susceptibility to infections and skin cancer. The review argued for recognizing skin aging as a disease due to its health implications and variability among individuals. It also discussed the psychological impact of skin aging and advocated for public health strategies to mitigate its progression. The document emphasized the complex interplay between skin aging, stem cell function, and immune response, suggesting potential interventions like targeting sirtuins to reverse aging effects.
6 citations,
July 2019 in “Experimental Dermatology” Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
6 citations,
January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
November 2023 in “International Journal of Medical Sciences” New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
June 2023 in “International journal of molecular sciences” Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
88 citations,
August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
December 2020 in “Daehanhanuihakoeji” Rumex japonicas Houttuyn ethanol extract helps increase hair growth and protect against hair damage.
May 2020 in “Authorea (Authorea)” Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.