research Effects of Topical Application of EGCG on Testosterone-Induced Hair Loss in a Mouse Model
Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
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research Follicular Swiss Cheese Pattern: Another Histopathologic Clue to Alopecia Areata
The study concluded that a 'Swiss cheese' pattern in hair follicles is a useful sign for diagnosing alopecia areata.
research Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia
Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
research Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response
Topical booster improves hair loss treatment effectiveness.
research The Expression of Insulin-Like Growth Factor 1 in Follicular Dermal Papillae Correlates with Therapeutic Efficacy of Finasteride in Androgenetic Alopecia
Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research The Effect of Plasma Rich in Growth Factors Combined with Follicular Unit Extraction Surgery for the Treatment of Hair Loss: A Pilot Study
Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
research Activity of Type 1 5α-Reductase Is Greater in the Follicular Infrainfundibulum Compared with the Epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region
Proteolytic enzymes damage hair follicles by detaching stem cells.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Hair Follicular Cell/Organ Culture in Tissue Engineering and Regenerative Medicine
Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
research Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent
About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
research High Response Rate to Bexxar in Advanced Stage Prior Treatment-Resistant Follicular Lymphoma
Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.
research HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis
HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
research Proliferative, Lymphocytic, Infundibular Mural Folliculitis and Dermatitis with Prominent Follicular Apoptosis and Parakeratotic Casts in Four Labrador Retrievers: Preliminary Description and Response to Therapy
A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.
research Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report
Enzyme injections can effectively treat epidermoid cysts without surgery.
research Transdermal Permeation of Drugs in Various Animal Species
Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to Control Propionibacterium Acnes
The conclusion suggests a new acne treatment that controls bacteria by reducing water in the skin's pores using sugar-like substances.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Minoxidil Increases 17β-Hydroxysteroid Dehydrogenase and 5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Balding Scalp
Minoxidil boosts enzymes that help hair growth.
research Advances in Understanding Hair Growth
Understanding glycans and enzymes that alter them is key to controlling hair growth.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Abnormal Liver Enzymes in Thymoma-Associated Multiorgan Autoimmunity
Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.
research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Pharmacological BACE1 and BACE2 Inhibition Induces Hair Depigmentation by Inhibiting PMEL17 Processing in Mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research pH Stimulus-Responsive Hybrid Nanoparticles: A System Designed for Follicular Delivery of Brazilian Plant-Derived 5-Alpha-Reductase Enzyme Inhibitors
New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.
research Dutasteride Nanoemulsion Preparation to Inhibit 5-Alpha-Hair Follicle Reductase Enzymes in the Hair Follicle: An Ex Vivo Study
The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.