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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

A patient with a skin condition had unusual scarring hair loss but improved with treatment.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

The gene Prss53 affects hair shape and bone development in rabbits.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

Fat under the skin can help hair grow longer, darker, and increase cell growth.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.

Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

The symposium concluded that environmental factors significantly contribute to skin aging.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.