205 citations,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
2 citations,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
17 citations,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
190 citations,
October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
55 citations,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
49 citations,
August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
6 citations,
May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
4 citations,
November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.
November 2024 in “Journal of Translational Internal Medicine” Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
11 citations,
April 2020 in “Life sciences” Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
11 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” New cell-based therapies may improve hair loss treatments in the future.
59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
58 citations,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
12 citations,
May 2019 in “Aesthetic Surgery Journal” Platelet-Rich Plasma and stem cell therapy can increase hair count and density, but the best method for preparation and treatment still needs to be determined.
11 citations,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
122 citations,
November 2010 in “Journal of Dermatological Science” Male pattern baldness involves hormones and cell signals affecting hair growth.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
26 citations,
October 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
6 citations,
December 2010 in “Journal of Cosmetic Dermatology” Apoptosis may contribute to hair loss in androgenetic alopecia.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
38 citations,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
13 citations,
September 2021 in “Current Issues in Molecular Biology” Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.