research Normal and Aging Hair Biology and Structure: Aging and Hair
Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
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research Multi-Layered Environmental Regulation on the Homeostasis of Stem Cells: The Saga of Hair Growth and Alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation
Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
research Current Evidence for Clinical Efficacy of Platelet-Rich Plasma in Aesthetic Surgery: A Systematic Review
The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
research Aging of Hair Follicle Stem Cells and Their Niches
Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
research Aging Skin and Non-Surgical Procedures: A Basic Science Overview
Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
research Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice
Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
research Histopathology of Aging of the Hair Follicle
Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
research Stem Cell Dynamics, Migration, and Plasticity During Wound Healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research Age-Dependent Loss of the Stemness and Antimicrobial Defense Function of Dermal Fibroblasts Is Mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Pharmacologic Interventions in Aging Hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Hair Greying and Its Palliative Management
Hair greying is seen as a sign of aging; temporary fixes like hair dye are used, but a balanced diet and hair care can help manage it.
research HSL Attenuates Follicular Oxidative Stress and Enhances Hair Growth in ob/ob Mice
HSL treatment speeds up hair growth and reduces oxidative stress in hair follicles of ob/ob mice.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Current Concepts in Aesthetic Endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
research Rosmarinus Officinalis and Skin: Antioxidant Activity and Possible Therapeutic Role in Cutaneous Diseases
Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.
research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research Expression of Anti-Aging Type-XVII Collagen (COL17A1/BP180) in Hair Follicle-Associated Pluripotent (HAP) Stem Cells During Differentiation
Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
research Hair Transplantation in Patients with Hair Loss or Scar Deformity in the Side Hairline After Midfacelifting Surgery
Hair transplantation effectively corrects hairline issues after midface-lifting surgery with high patient and physician satisfaction.
research Investigation by Imaging Mass Spectrometry of Biomarker Candidates for Aging in the Hair Cortex
Certain molecules in hair change with age and could be used for cosmetic treatments.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research Aesthetic Strategies for the Aging Asian Face
The document suggests using fat grafting and laser therapy to improve the aging Asian face and hair restoration techniques tailored to Asian hair characteristics, emphasizing natural results and cultural sensitivity.
research Male Pattern Alopecia: Impact on Self-Esteem and Evolution of Hair Restoration Surgery
The document concludes that advancements in hair restoration surgery have led to more natural results and patient satisfaction, with hope for future improvements in treatment.