July 2025 in “International Journal of Biological Macromolecules” A new microneedle system effectively delivers finasteride to treat hair loss.
31 citations
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September 2014 in “Journal of Pharmaceutical Sciences” This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.
3 citations
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July 2013 in “Journal of Cutaneous Pathology” This case report describes a 56-year-old woman whose nonscarring alopecia, consistent with alopecia areata with follicular mucinosis, resolved completely after treatment with oral prednisone.
9 citations
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January 2002 in “Dermatology” This study found that cutaneous myxomas showed decreased CD44 expression in follicular epithelial proliferations, which may be related to abnormal hyaluronate accumulation in these lesions.
5 citations
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July 2019 in “Photodiagnosis and photodynamic therapy” This study reports a case of a 59-year-old female with refractory follicular mucinosis and diffuse scalp alopecia who achieved complete clinical remission following treatment with a combination of topical tacalcitol and photodynamic therapy.
1 citations
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February 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This case report presented a 52-year-old man with cutaneous focal mucinosis, exhibiting rare follicular induction of the epidermis, underscoring the importance of recognizing this association in differential diagnoses.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, authors argue that Hair Booster by Dantura Botanics supports hair regeneration by addressing internal biochemical deficiencies without relying on conventional hormonal or chemical treatments, and it is part of a broader micronutrient-based, terrain-corrective model for reversing scalp degeneration.
January 2025 in “Expert Opinion on Drug Delivery” This study discusses the limitations of current FDA-approved treatments for androgenic alopecia, noting significant sexual side effects with oral finasteride and formulation challenges with topical minoxidil, and highlights the potential of nanocarriers to improve drug delivery to hair follicles.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This article explores the potential of Hair Booster by Dantura Botanics, a micronutrient formulation aimed at restoring the biochemical environment needed for hair regeneration, and describes clinical observations suggesting that significant scalp degeneration can be reversed when follicles receive adequate micronutrients, according to this study.
77 citations
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January 2015 in “International Journal of Biological Macromolecules” This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.
211 citations
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June 2012 This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.
67 citations
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August 2013 in “International Journal of Cosmetic Science” This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
7 citations
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August 2021 in “Pharmaceutics” This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.
3 citations
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March 2014 in “Veterinary dermatology” This study reports the first documentation of mural, mucinotic, isthmus folliculitis alopecia in Norwegian puffin dogs, noting that ciclosporin treatment led to remission while other treatments were less effective.
This chapter reviews various fungal skin diseases affecting cattle but does not report new research findings; it focuses on rare, inherited, and congenital conditions like follicular dysplasia and cutaneous asthenia.
April 2014 in “The FASEB Journal” This study found that maternal hephaestin knockout in mice leads to neonatal hair loss, likely due to low iron levels in the mother's milk.
May 2026 in “Therapeutic Delivery” This study found that applying a dutasteride-loaded liposome formulation to damp rat skin nearly doubled the drug's follicular accumulation compared to dry skin, suggesting scalp hydration status may significantly impact the drug's topical delivery, especially in follicle-rich areas.
March 2024 in “Bioimpacts” In this study, curcumin-loaded nanoparticles with a size of 400 nm showed optimal accumulation in human hair follicles after seven days, although mouse models differed significantly in penetration and retention, indicating limitations in their suitability for follicular drug delivery studies.
16 citations
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November 2023 in “Scientific Reports” This study developed a niosomal delivery system loaded with tretinoin and bicalutamide, optimized for follicular targeting in acne management, showing promising accumulation in hair follicles in animal models.
This study found that nanostructured lipid carriers significantly improved the targeted delivery of latanoprost and minoxidil to pilosebaceous units in porcine skin, with latanoprost showing notably higher accumulation.
33 citations
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October 2016 in “European Journal of Pharmaceutical Sciences” This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
10 citations
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January 2014 in “Journal of Pharmaceutical Sciences” This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.
26 citations
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February 2020 in “International Journal of Biological Macromolecules” This study demonstrates that massage significantly enhances the follicular targeting of dutasteride-loaded nanocapsules, increasing drug accumulation in hair follicles by up to 5 times.
32 citations
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March 2013 in “Journal of Pharmaceutical Sciences” This study observed that iontophoresis significantly improved the delivery of minoxidil sulfate to hair follicles compared to passive methods, suggesting potential benefits for alopecia treatment.
November 2025 in “Cureus” In this case report, researchers describe a 21-year-old male with a forehead lesion exhibiting typical clinical and histopathologic signs of follicular mucinosis, contributing to understanding of this rare condition through a detailed case analysis and associated literature review.
15 citations
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February 2023 in “Colloids and surfaces. B, Biointerfaces” In this study using a porcine skin model, the researchers reported that smaller curcumin nanocrystals in xanthan gum gel showed higher passive skin penetration, while larger particles achieved deeper follicular accumulation.
32 citations
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November 2004 in “Journal of pharmaceutical sciences” This study quantifies the follicular uptake of tea tree oil in bovine udder skin, with microemulsion showing the highest concentration among different formulations tested.
44 citations
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April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
April 2026 in “Clinical Dermatology Review” In this study, patients with keratosis pilaris exhibited significant quality of life impairment, with histopathology and dermoscopy revealing consistent skin and hair changes.