31 citations,
September 2006 in “International journal of gynaecology and obstetrics” New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
1 citations,
March 2022 in “Clinical and Experimental Obstetrics & Gynecology” Ovarian volume is significantly related to higher levels of certain hormones in Korean women with PCOS.
45 citations,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
4 citations,
November 2016 in “Archives of Endocrinology and Metabolism” Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.
49 citations,
May 2018 in “Endocrine” Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
56 citations,
April 1998 in “Steroids” Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
70 citations,
March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
April 2020 in “BMC endocrine disorders” A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
19 citations,
October 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The diagnosis of polycystic ovary syndrome (PCOS) requires a detailed patient history, ultrasound scanning, hormone level checks, and assessments of ovulation, obesity, and insulin resistance. It's a variable condition that needs individualized management and is a significant risk factor for type 2 diabetes.
1 citations,
July 2017 in “Clinical research in dermatology” Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
12 citations,
January 2016 in “Journal of Assisted Reproduction and Genetics” Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.
2 citations,
July 2022 in “Frontiers in Medicine” Combining minoxidil with microneedling or spironolactone is more effective for female hair loss than using minoxidil alone.
21 citations,
January 1991 in “Dermatology” Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.
The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.
1 citations,
October 2022 in “International journal of endocrinology” Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
3 citations,
January 2007 in “Elsevier eBooks” The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
74 citations,
January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
1 citations,
January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
5 citations,
September 2021 in “Dermatology Reports” Skin problems like acne and excess hair in PCOS are common and linked to being overweight.
March 2023 in “European journal of internal medicine” The patient's long-term symptoms were due to Sheehan's syndrome, which improved with hormone therapy.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
19 citations,
February 2012 in “International Journal of Urology” In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.
72 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
9 citations,
October 2018 in “Medical Science Monitor” Lowering certain hormone levels improves treatment for hair loss in young men.
November 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.