August 2016 in “Journal of evolution of medical and dental sciences” This study describes the clinical profile of acne vulgaris in patients from a tertiary care hospital, noting a male predominance and frequent occurrence of post acne hyperpigmentation.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.
April 2019 in “Advances in integrative medicine” This study found that the highest rebound value in concrete with high volume slag occurs with 40% slag content, 10–20 mm basalt aggregates, and greater carbonation depth.
48 citations
,
September 2013 in “Oncologist” This study reported that alopecia is a common but often underreported side effect of endocrine-based cancer therapies, with tamoxifen showing the highest incidence of hair loss among analyzed treatments.
19 citations
,
March 1987 in “International Journal of Dermatology” This study reports that cimetidine treatment resulted in good to excellent hair regrowth in 70% of the small group of women with androgenetic alopecia, with no major side effects observed.
13 citations
,
April 2020 in “Dermatology and therapy” This systematic review assessed cyclosporine's effectiveness with or without corticosteroids for treating alopecia areata, finding combined therapy more effective and with a lower recurrence rate than monotherapy, especially for severe cases, though results varied by alopecia type.
3 citations
,
January 1996 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” In this study, a 33-year-old HIV-infected man experienced alopecia areata after beginning zidovudine therapy, which reversed upon discontinuation.
1 citations
,
May 2025 in “The Journal of Rheumatology” This study reviewed how Anifrolumab, though often used in real-world settings for SLE patients with neurological symptoms, showed varying effectiveness and required cautious monitoring for adverse effects like thrombocytopenia and cerebrovascular events.
1 citations
,
July 2021 in “Curēus” This case report describes a rare occurrence of lichen planopilaris in a nine-year-old child, emphasizing the need for awareness of this condition in the pediatric population.
1 citations
,
June 2020 in “Actas Dermo-Sifiliográficas” This review discusses emerging therapies for androgenetic alopecia, including topical finasteride, oral minoxidil, and intradermal dutasteride, and reports no clinical results; the authors highlight changes in treatment approaches.
December 2022 in “Curēus” This case report describes a 5-year-old girl with atrichia with papular lesions, whose diagnosis was confirmed through genetic testing identifying mutations in the hairless gene.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.
77 citations
,
July 2012 in “Journal of Investigative Dermatology” The researchers observed that overexpression of Wnt10b in a mouse model can induce hair follicle regeneration by switching follicles from the resting phase to the growth phase via the Wnt-β-catenin signaling pathway.
330 citations
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December 2009 in “Cell stem cell” This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.
184 citations
,
December 2018 in “Nature Communications” This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.
124 citations
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August 1994 in “Journal of Investigative Dermatology” This study found that applying dexamethasone to mice induced catagen-like follicle changes significantly earlier and more consistently than a vehicle, such changes being useful for studying hair follicle regression.
117 citations
,
March 2017 in “Nature Communications” This study shows that macrophage-induced TNF signaling can activate hair follicle stem cells and promote new hair follicle formation after wounding by regulating AKT/β-catenin pathways.
103 citations
,
November 2014 in “Journal of Cell Biology” This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
91 citations
,
April 2011 in “Journal of Ethnopharmacology” This study found that Polygonum multiflorum extract may promote hair growth by inducing the anagen phase in the resting hair follicles of mice.
90 citations
,
January 1979 in “International review of cytology” This chapter reviews the complexity of hair and wool follicle formation, emphasizing the importance of cytological studies to understand the relationship between cellular components.
87 citations
,
January 2016 in “Development” This study suggests that the postnatal loss of hair follicle formation in wounds may be due to elevated Wnt/β-catenin activation in the dermis, affecting fibroblast function in mice.
79 citations
,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that procyanidin oligomers, particularly dimers and trimers, significantly promoted hair growth in mice and hair epithelial cell cultures, suggesting potential use as hair growth agents.
75 citations
,
October 2016 in “Genes & Development” This study found that Sonic Hedgehog secreted by hair follicle transit-amplifying cells is essential for dermal adipogenesis and hair follicle growth by acting on adipocyte precursors.
70 citations
,
April 2017 in “Lasers in surgery and medicine” This study found that blue light at a wavelength of 453 nm promoted hair growth ex vivo, potentially through interacting with OPN3 receptors in human hair follicles.
61 citations
,
June 2014 in “Scientific Reports” This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.
57 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the vitamin D receptor is crucial for initiating the postnatal hair follicular cycle in mice, preventing alopecia associated with its inactivation.
52 citations
,
October 2012 in “Journal of Dermatological Science” This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.
51 citations
,
November 2010 in “Dermatologic Surgery” This study measured the lengths and depths of different portions of occipital scalp hair follicles and suggested cutting below 1 mm for hair regeneration procedures to avoid damaging the bulge zone.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.
40 citations
,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study visualized mitochondrial metabolism in cultured bovine hair follicles and plucked human hairs, finding that ROS and mitochondrial polarization correlate in specific hair follicle regions, particularly near keratin deposition sites.