April 2018 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” This study observed that patients with different types of alopecia exhibited variable epidermal thickness and consistent dermal changes, including hair follicle destruction and lymphohistiocytic infiltrates, which may suggest inflammation.
9 citations
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May 2013 in “JAMA Dermatology” This report details a case of extensive leukotrichia induced by dasatinib in a patient with refractory chronic myelogenous leukemia.
2 citations
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May 2023 in “Journal of Immunotherapy” In this case study, a 65-year-old male with hepatocellular carcinoma treated with the PD-1 inhibitor Sintilimab developed alopecia universalis alongside significant tumor regression and complete remission, highlighting a rare immune-related adverse event with effective anti-tumor outcomes.
October 2025 in “JEADV Clinical Practice” This systematic review found very weak evidence supporting the use of minoxidil as an adjunctive treatment for traction alopecia, with improvements noted from 3 months onwards, primarily based on limited case reports and retrospective case series.
4 citations
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May 2021 in “The American Journal of Surgical Pathology” This study suggests that cutaneous lymphadenoma is a distinct benign lymphoepithelial tumor characterized by androgen receptor expression, hair follicle stem cell markers, and common EGFR gene mutations.
18 citations
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April 2022 in “Frontiers in bioengineering and biotechnology” This study found that gelatin microspheres delivering adipose-derived stem cells significantly accelerated diabetic wound healing in rats, suggesting a promising approach for enhancing cell-based therapies.
June 2025 in “Journal of Kufa for Chemical Sciences” In this study, researchers observed increased hormone levels such as testosterone and LH in both obese and non-obese women with Polycystic Ovary Syndrome, but concluded that the enzyme 3βHSD shows poor diagnostic value for PCOS compared to healthy women.
February 2022 in “Research Square (Research Square)” In this cell-based study, researchers found that certain nutraceuticals combined with tamoxifen may influence estrogen receptor expression, potentially offering a protective effect and promoting hair growth during breast cancer therapy.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no elevation of serum DHEA-S levels in men with androgenetic alopecia and observed no correlation between DHEA-S levels and the clinical stage of the condition.
January 2022 in “Wiadomości lekarskie (Warsaw Poland)” This study found that Methylsulfonylmethane significantly reduced hair loss and enhanced hair growth and follicle number in male mice, attributed to its antioxidant and anti-inflammatory properties.
October 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no correlation between the clinical stage of androgenetic alopecia and serum levels of dehydroepiandrosterone-sulfate, contrasting earlier findings and supporting theories about alternative androgen sources in hair follicles.
22 citations
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July 1987 in “Transplantation” This study found that topical cyclosporine significantly prolonged the survival of skin allografts in a rat model, with maximum effectiveness achieved through local direct application.
1 citations
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December 2017 in “Acta biomedica scientifica” This study observed that 30% of women with polycystic ovary syndrome had androgenic alopecia, suggesting it is a prevalent but unreliable marker of hyperandrogenism.
1 citations
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April 2016 in “Journal of Microbiology Biotechnology and Food Sciences” This study found that caraway essential oil inhibited Staphylococcus aureus strains isolated from patients with furunculosis, suggesting it may serve as an alternative antibacterial agent for supporting treatment.
August 2026 in “International Journal of Research in Ayurveda and Pharmacy” This review discusses the Ayurvedic concept of Indralupta, resembling alopecia areata, and highlights dietary therapy's potential role in holistic prevention and management, while reporting no new clinical results.
June 2026 in “International Journal of Drug Delivery Technology” This study highlights the potential of polymeric micelles in enhancing the targeted delivery and efficacy of treatments for androgenetic alopecia, by offering improved retention on the scalp, extended release, and reduced systemic side effects compared to conventional therapies like minoxidil and finasteride.
17 citations
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June 2017 in “Journal of pharmaceutical sciences” This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.
39 citations
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December 2001 in “JNCI: Journal of the National Cancer Institute” This study found that enhanced expression of the Sonic hedgehog gene via an adenovirus vector accelerated hair regrowth in mice with chemotherapy-induced alopecia.
505 citations
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October 2011 in “Journal of clinical oncology” This phase I study found that MK-2206 was well tolerated and demonstrated evidence of AKT signaling blockade in patients with advanced solid tumors, with the maximum-tolerated dose established at 60 mg.
47 citations
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June 2016 in “JAMA Dermatology” This study suggests men with early androgenetic alopecia might have hormonal profiles similar to women with polycystic ovarian syndrome, potentially indicating risk for related health complications.
July 2025 in “Russian Journal of Skin and Venereal Diseases” This article discusses the characteristics, diagnosis, and clinical presentation of different variants of lichen planopilaris on the scalp, with emphasis on cicatricial alopecia and the importance of clinical and trichoscopic monitoring; it presents no new clinical results.
13 citations
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August 2020 in “Frontiers in Cell and Developmental Biology” This study found that Twist1 and Tcf4 synergistically regulate the hair follicle induction ability of dermal papilla cells by forming a complex with β-catenin, enhancing their biological properties.
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
24 citations
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February 2011 in “The American journal of pathology” This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.
1 citations
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January 2010 in “International journal of medicinal mushrooms” This study found that Ganoderma lucidum fruiting body powder improved cholesterol profiles and hair follicle health in rats exposed to a tumor-promoting agent, suggesting potential chemopreventive properties against skin abnormalities.
3 citations
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January 2016 in “Biotechnology and Bioprocess Engineering” This animal study found that Laminaria japonica mixed with insulin-like growth factor-1 significantly promoted hair growth in mice, suggesting its potential use for treating alopecia pending further clinical trials.
June 2024 in “Skin Research and Technology” In this study, patients with androgenetic alopecia who received type A botulinum toxin treatment showed increased follicle width and length at the vertex and left frontal area over three months, but no significant changes in follicle or hair count compared to the control group.
April 2021 in “Journal of Investigative Dermatology” This study explored the use of an AI-driven device, HairMetrix, to quantitatively assess the effects of PRP treatments on scalp health in two Caucasian women with androgenetic alopecia, reporting increases in average hair width and follicle count after one treatment.
April 2022 in “Journal of advances in medicine and medical research” This study found that applying topical minoxidil 5% twice daily for 24 weeks increased hair density and width in men with androgenetic alopecia, although the change in clinical hair grading was not statistically significant.
4 citations
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March 1979 in “Journal of Animal Science” This study suggests that feeding pregnant mares protein blocks with urea is as effective as hand-fed protein supplements in supporting hair follicle development and protein status.