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The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

The upper dermal sheath can regenerate hair in rats.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

A 14-year-old boy is the youngest person reported with a rare, benign tumor related to hair follicles, usually found in older people.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Understanding hair follicles through various models can help develop new treatments for hair disorders.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.

Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.

The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Valproic acid may help hair grow and could be a safe treatment for hair loss.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

Rumex japonicus extract may promote hair growth more effectively than Minoxidil.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Herbal hair oil made with natural ingredients helps reduce hair loss, dandruff, and graying.

Scientists can now create skin with hair by reprogramming cells in wounds.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

Many dermatologists in Saudi Arabia recommend vitamins and minerals for hair loss, often based on personal experience rather than strong evidence.