August 2023 in “Molecules and Cells” Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
April 2023 in “Journal of Investigative Dermatology” Covering a wound can stop hair growth by promoting scarring, but boosting a process called Wnt signaling can help hair grow back even when the wound is covered.
4 citations,
March 2022 in “Pharmaceutics” Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
24 citations,
September 2018 in “Lasers in Surgery and Medicine” Multiphoton microscopy can non-invasively tell apart scarring from non-scarring hair loss and could aid in treatment.
15 citations,
July 2017 in “PubMed” Injecting a mix of human skin and hair cells into mice can grow new hair.
13 citations,
April 2001 in “International Journal of Dermatology” Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
3 citations,
April 2010 in “The American Journal of Dermatopathology” Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
March 2024 in “Research Square (Research Square)” Twist2 is essential for proper skin healing and hair growth in developing mice.
January 2010 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Chemical relaxers may cause scarring alopecia in black women.
24 citations,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
November 2024 in “Journal of Drugs in Dermatology” PRP shows promise for scarring alopecia but needs more research before replacing current treatments.
April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
July 2022 in “المجلة العراقية للصيدلة” Most women with excessive hair growth (hirsutism) also experience a common type of non-scarring hair loss called Androgenetic alopecia with telogen effluvium.
July 2021 in “British Journal of Dermatology” A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
May 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.
176 citations,
June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
29 citations,
January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
October 2022 in “IntechOpen eBooks” Hair loss due to scarring can be treated by reducing inflammation, removing scar tissue, and transplanting hair. The Follicular Unit Extraction technique is effective but requires skill and time. Future focus should be on scar-less healing methods.
112 citations,
July 1998 in “Journal of Investigative Dermatology” Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
April 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
122 citations,
April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
October 2024 in “Frontiers in Nutrition” Vitamin D deficiency is common in people with certain types of hair loss, like alopecia areata and female pattern hair loss.
August 2021 in “Chinese journal of burns” Combining FUE with rb-bFGF and minoxidil is more effective and has fewer side effects than FUE alone for treating hair loss.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
3 citations,
January 2019 in “Skin appendage disorders” A woman with a rare scalp lymphoma had unusual hair loss after treatment.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.