97 citations,
September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
92 citations,
September 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
48 citations,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
41 citations,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
29 citations,
September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
24 citations,
September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
23 citations,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
15 citations,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
13 citations,
July 2019 in “Journal of Dermatological Science” Increasing alkaline phosphatase in human skin cells helps to grow more hair.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
9 citations,
January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
8 citations,
January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
5 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
2 citations,
November 2022 in “Scientific reports” Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
April 2017 in “Journal of Dermatological Science” Certain flavonoids can improve the growth of pigmented hair in mice.
6 citations,
June 2012 in “PloS one” A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
5 citations,
December 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
36 citations,
January 2017 in “Stem Cells International” A special stem cell fluid can speed up wound healing and hair growth in mice.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
32 citations,
June 2021 in “Frontiers in Pharmacology” The hydrogel speeds up burn wound healing and promotes tissue regeneration.
18 citations,
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Different parts of the body have unique immune characteristics in their skin.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
1 citations,
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Blocking IL-17 signaling can delay skin aging and improve skin and hair health.
September 2023 in “Membranes” 3D-printed membranes with smart sensors can greatly improve tissue healing and have many medical applications.