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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Melatonin may reduce skin damage caused by X-rays in rats.

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Skin organoids are a promising new model for studying human skin development and testing treatments.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

Spironolactone may help enlarge a small breast linked to Becker's nevus.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.