30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
3 citations,
January 2021 in “Skin appendage disorders” Hair color is not a risk factor for developing alopecia areata.
2 citations,
July 2022 in “Frontiers in Medicine” Combining minoxidil with microneedling or spironolactone is more effective for female hair loss than using minoxidil alone.
2 citations,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
1 citations,
March 2022 in “Daehanhanuihakoeji” Artemisia sieversiana extract may help prevent hair loss and promote hair growth.
1 citations,
January 2019 in “Skin appendage disorders” A woman's sudden hair loss three years after a bone marrow transplant was a sign of chronic graft-versus-host disease but improved with treatment.
May 2024 in “FEBS open bio” Annurca apple extract may help treat hair loss and protect against oxidative stress.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of TET2 increases the risk of skin and oral cancer.
April 2021 in “Journal of Investigative Dermatology” IL-15 helps protect hair follicles from immune attacks and encourages hair growth.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
January 2012 in “Human health handbooks” Low-level light therapy is FDA-approved for male pattern hair loss, increases hair count and strength, and is considered safe for use.
October 2022 in “International Journal of Research in Dermatology” Hormonal imbalances contribute to female hair loss, and trichoscopy is a useful diagnostic tool.
April 2018 in “Journal of Investigative Dermatology” Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
234 citations,
February 2001 in “British Journal of Dermatology” FPHL affects hair density and diameter, causing visible hair loss in older women.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
102 citations,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
27 citations,
February 2017 in “Biomedicine & Pharmacotherapy” White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
21 citations,
November 2017 in “Archives of Dermatological Research” Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
20 citations,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
14 citations,
July 2015 in “Journal of Cosmetic Dermatology” Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
11 citations,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
11 citations,
July 2018 in “AJGP” Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
10 citations,
January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
9 citations,
October 2021 in “Journal of Cosmetic Dermatology” Microneedling is an effective and minimally invasive treatment for hair loss.
9 citations,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
8 citations,
October 2021 in “Experimental cell research” Engineered vesicles from macrophages help hair growth in mice and humans.
6 citations,
June 2011 in “Journal of The American Academy of Dermatology” Iron deficiency might be linked to hair loss, but more research is needed.