173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
9 citations,
April 2019 in “International journal of molecular sciences” Human hair grows better in a special gel that mimics skin.
Ganoderma lucidum extract may help treat stress-related hair loss.
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
January 2008 in “Linchuang pifuke zazhi” Betamethasone activates and increases the growth of certain skin cells from hair follicles.
125 citations,
September 2001 in “The FASEB Journal” Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
18 citations,
February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
November 2024 in “Genomics” Melatonin boosts hair growth in cashmere goats by helping certain cells multiply.
1 citations,
September 2022 in “Journal of dermatological science” Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.
27 citations,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
April 2013 in “Developmental Cell” Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
61 citations,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
22 citations,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
April 2015 in “Plastic and Reconstructive Surgery” Activating TLR3 helps improve skin and hair follicle regeneration after wounds.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
124 citations,
January 2012 in “Journal of Allergy and Clinical Immunology” Endocannabinoids help control mast cell activity in human skin.
78 citations,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
28 citations,
December 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Cancer treatment drugs can cause permanent hair loss by damaging hair follicle stem cells, but a specific inhibitor might reverse this effect.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
December 2023 in “Journal of Food Science and Nutrition” Rosehip Seed Oil may help hair grow by activating important growth pathways and increasing hair follicle size in mice.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
137 citations,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
33 citations,
April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
16 citations,
May 2011 in “The Journal of clinical investigation/The journal of clinical investigation” Some skin tumors may start from hair follicle stem cells.
February 2025 in “International Journal of Molecular Sciences” RORA plays a key role in controlling seasonal hair molting by affecting hair follicle cell activity.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.