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    Glossary FOL-005

    peptide treatment promoting hair regrowth by modulating signaling pathways

    FOL-005 is a peptide-based treatment developed for hair loss, specifically targeting conditions like androgenetic alopecia. It works by modulating the Wnt/β-catenin signaling pathway, which is crucial for hair follicle development and growth, thereby promoting hair regrowth and reducing hair thinning.

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    1. A novel microparticle based formulation for topical delivery of FOL-005, a small peptide Journal of Pharmaceutical Sciences · 2022 · 1 citations
    2. 128 Analysis of mice skin distribution using MALDI-MSI after subcutaneous injections of a potent novel peptide hair growth promoter, FOL-005 Journal of Investigative Dermatology · 2018
    3. 201 Analysis of mice skin distribution using MALDI-MSI after subcutaneous injections of a new potent novel inhibitor of human hair growth, FOL-005 Journal of Investigative Dermatology · 2016
    4. 695 Using MALDI-MSI analysis to study distribution of FOL-005, a potent, novel inhibitor of human hair growth, after subcutaneous injection in mice Journal of Investigative Dermatology · 2016
    5. An osteopontin‐derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor‐7 production in outer root sheath keratinocytes British Journal of Dermatology · 2019 · 19 citations
    6. 129 Genetic transformation of keratoacanthoma-type cutaneous squamous cell carcinoma following intralesional chemotherapy Journal of Investigative Dermatology · 2018 · 2 citations
    7. Osteopontin regulatory functions in the hair follicle open a therapeutic approach for hypertrichosis British Journal of Dermatology · 2019
    8. 130 Expression of nidogen1 in basal cell carcinoma Journal of Investigative Dermatology · 2018
    9. 131 Mutational landscape of extramammary Paget disease Journal of Investigative Dermatology · 2018
    10. 1371 FGF7-dependent inhibition of human hair growth byan osteopontin-derived peptide: A novel solution for hirsutism and hypertrichosis? Journal of Investigative Dermatology · 2018
    11. 682 Identification of novel potential therapeutic targets by comparative transcriptomic profiling of physiological and pathological skin wounds ex vivo Journal of Investigative Dermatology · 2024
    12. Clobetasol propionate 0.05% under occlusion in the treatment of alopecia totalis/universalis Journal of the American Academy of Dermatology · 2003 · 146 citations
    13. Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride International Journal of Dermatology · 2014 · 36 citations
    14. Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis Pharmacological Research · 2024 · 5 citations
    15. Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study<sup>1</sup> The Journal of Clinical Endocrinology and Metabolism · 1998 · 633 citations
    16. Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study The Journal of Clinical Endocrinology and Metabolism · 1998 · 378 citations
    17. Tratamento da alopecia areata com corticóide tópico: estudo prospectivo randomizado duplo cego em crianças * Therapy of alopecia areata with topical corticosteroid: prospective double-blind controlled assay in children * 2003
    18. The effect of metformin on hirsutism in polycystic ovary syndrome European journal of endocrinology · 2002 · 90 citations
    19. Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men Journal of Endocrinological Investigation · 2021 · 5 citations
    20. Minimizing injury to the donor area in follicular unit extraction (FUE) harvesting Journal of Cosmetic Dermatology · 2016 · 13 citations
    21. Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of prostaglandin F2α receptor activation Pharmacological Reports · 2026
    22. TREATMENT OF ALOPECIA AREATA Dermatologic clinics · 1996 · 48 citations
    23. The patch assay reconstitutes mature hair follicles by culture-expanded human cells Regenerative Medicine · 2017 · 11 citations
    24. Performance of Chlorhexidine and Ophytrium-Containing Shampoo and Mousse in Dogs with Cutaneous Yeast Imbalance Open Journal of Veterinary Medicine · 2024
    25. Dutasteride Micro-Injections in Androgenetic Alopecia Dermatología Cosmética, Médica y Quirúrgica · 2019
    26. Prognostic factors that affect the response to topical treatment in patchy alopecia areata Journal of The European Academy of Dermatology and Venereology · 2012 · 13 citations
    27. Scalp involvement in pemphigus: a prognostic marker Advances in Dermatology and Allergology · 2017 · 10 citations
    28. Abstracts Experimental Dermatology · 2018 · 3 citations
    29. Effect of cosmetic hair treatment and natural hair colour on hair testosterone concentrations PloS one · 2023 · 1 citations
    30. Is the Addition of Oral Biotin to PRP More Beneficial for Treating Male Pattern Hair Loss Compared to PRP Alone? A Randomized Control Trial Journal of Pakistan Association of Dermatologists · 2025