59 citations
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July 2020 in “Journal of The American Academy of Dermatology” This study concluded that oral minoxidil is an effective and well-tolerated alternative to topical minoxidil for healthy patients struggling with application-related compliance issues.
50 citations
,
June 1999 in “Annals of Oncology” This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.
48 citations
,
November 1992 in “International Journal of Dermatology” This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.
45 citations
,
November 1979 in “British Journal of Dermatology” This report describes a case of hypertrichosis associated with minoxidil use and suggests that nearly all patients on this drug may experience this side effect.
39 citations
,
February 2021 in “Journal of The American Academy of Dermatology” In this study, low-dose oral minoxidil for hair loss was associated with infrequent systemic adverse effects, and only 1.7% of patients discontinued treatment due to these effects.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
5 citations
,
July 2019 in “Atlas of the Oral and Maxillofacial Surgery Clinics” This article discusses challenges and limitations of using simple tissue mechanics for repairing head and neck skin defects in trauma and does not report new findings; it highlights potential problems with routine methods.
5 citations
,
March 2016 in “Medical journal, Armed Forces India” This report describes a case of refractory shock and pulmonary edema resulting from the accidental ingestion of topical minoxidil, highlighting a rare instance of poisoning.
3 citations
,
April 2012 in “Internal and Emergency Medicine” In this case report, a 14-year-old girl with nephrotic syndrome developed large edematous striae distensae due to high-dose steroid use and rapid body size increase from edema fluid accumulation.
2 citations
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June 1983 in “Proc., Annu. Meet., Air Pollut. Control Assoc.; (United States)” This case study reports that ingestion of topical minoxidil, used for hair loss, can cause severe circulatory shock and acute pulmonary edema, necessitating immediate medical intervention with fluids and vasopressors.
1 citations
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June 2012 in “Revista Brasileira de Cirurgia Plástica” In this study, the authors reported that frontal rhytidectomy with a pre-hairline incision effectively reduces a long forehead in select patients, with patients feeling the benefits outweighed the visibility of the scar.
1 citations
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May 2007 in “International Journal of Dermatology” Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
August 2026 in “LUMEN ET VIRTUS” In this study, low-dose oral minoxidil for androgenetic alopecia was generally safe, showing small average changes in blood pressure and heart rate with infrequent cardiovascular issues, though monitoring is essential, especially in patients with conditions like hypertension or arrhythmias.
June 2026 in “arXiv (Cornell University)” This study investigated the dynamic mechanical properties of fluid-immersed elastic hair beds under oscillatory shear flows, revealing a nonlinear response influenced by driving frequency and amplitude, which impacts mechanosensory signaling stability in biological processes like vasodilation and ciliary remodeling.
November 2025 in “Nature Communications” This study used a 3D live imaging system to map cell dynamics in human hair follicles, revealing patterns of cell movement and division that help explain hair fiber extrusion during hair growth.
May 2025 in “Current Drug Safety” In this case study, a 17-year-old male using topical minoxidil 5% for beard growth developed peripheral edema, which resolved after discontinuing the drug, highlighting a rare but significant systemic side effect of minoxidil's use.
March 2025 in “Journal of Clinical Medicine” This study reviewed adverse events associated with low-dose oral minoxidil for treating alopecia, finding hypertrichosis and fluid retention as common, typically manageable side effects without needing treatment discontinuation.
November 2024 in “Cureus” In this case report, a 24-year-old male experienced severe vasoplegic shock after ingesting a large amount of minoxidil solution, requiring an unprecedented 180 hours of norepinephrine support for blood pressure maintenance, highlighting the need for extensive supportive care following minoxidil intoxication.
September 2024 in “Journal of Cosmetic Dermatology” This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.
June 2024 in “European Journal of Clinical and Experimental Medicine” This review found that oral minoxidil, used for treating androgenetic alopecia, can cause dose-dependent fluid retention and weight gain, but remains safe for most patients; a diuretic might be needed if significant weight gain occurs.
February 2024 in “Frontiers in physiology” This review highlights the important role of lymphatic vessels in skin regeneration and their interaction with skin stem cells, emphasizing recent research advancements and potential implications for managing skin diseases.
November 2023 in “Circulation” In this case report, a 59-year-old man experienced recurrent pericardial effusion linked to minoxidil, with serologic indications of drug-induced lupus erythematosus, underscoring the need for clinicians to consider this rare complication of widespread minoxidil use.
September 2023 in “Translational medicine reports” This case study reported that an 18-year-old woman ingested a large amount of topical minoxidil, leading to symptoms like low blood pressure, increased heart rate, and elevated liver enzymes, but recovered fully after treatment. Minoxidil toxicity may rarely cause abnormal liver enzyme levels.
August 2023 in “JAAD International” This study evaluated low dose oral minoxidil as a treatment for female pattern hair loss but reports no new clinical results.
September 2022 in “JAAD Case Reports” This case report discusses rare but serious cardiac complications, including pericarditis and edema, observed with low-dose oral minoxidil for hair loss, highlighting the need for cautious prescribing, especially in high-risk patients.
August 1978 in “Dicp-The annals of pharmacotherapy” Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.
July 2022 in “Hair transplant forum international” This case report describes a 27-year-old male who developed a frontal scalp hematoma after platelet-rich plasma therapy and suggests that topical minoxidil may contribute to this side effect.
188 citations
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December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
125 citations
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December 2016 in “Molecules” This review discusses the extraction, purification, modification, and biological activity of polysaccharides from Traditional Chinese Medicine and reports no new research findings.
50 citations
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December 2022 in “Food Chemistry Advances” This review discusses diosgenin's potential benefits for several chronic diseases and emphasizes extraction and quantification techniques, but reports no clinical findings.