November 2024 in “International Journal of Women’s Dermatology” In this study of a Colombian sample, the researchers found that while sex, alopecia location, and symptoms aligned with global reports, age at presentation, tobacco use, and use of wigs and dyes were different from those noted in other countries.
This study reviews the diverse clinical presentations of tinea capitis, such as gray patches, a "black dot" appearance, and kerion, highlighting its complex differential diagnosis with conditions like alopecia areata and psoriasis.
August 2023 in “Journal of Cosmetic Dermatology” This study found that intradermal QR678 Neo® therapy improved scalp condition in men and women with seborrheic dermatitis unresponsive to standard treatments, reducing flaking and inflammation after eight sessions, with high patient satisfaction reported.
January 2023 in “Acta medica Philippina” This study found that ethyl acetate extract of Carica papaya flowers exhibited the highest antioxidant and 5α-reductase inhibitory activities, suggesting potential hair growth-promoting properties.
February 2021 in “Aesthetic Cosmetology and Medicine” This study suggests that glycosaminoglycans, like hyaluronic acid obtained biotechnologically, are safe for topical cosmetic use, enhancing skin and hair conditions by supporting cell renewal, stimulating hair growth, and aiding in the treatment of scalp issues such as seborrhea and androgenetic alopecia.
May 2020 in “Research, Society and Development” This study suggests that mutamba fruit, regardless of maturation stage, could be valuable in the food industry due to its high soluble solids, vitamin C, and mineral content.
September 2019 in “Journal of Investigative Dermatology” This study found that a combination of botanical extracts from Pisum sativum and Salvia hispanica reduced oxidative damage, re-balanced scalp oiliness, and improved scalp hydration and barrier function after pollution exposure.
April 2019 in “Journal of parasitic diseases” This case report describes a male Persian cat with Cheyletiella spp. infestation causing alopecia and pruritus, which was successfully treated using ivermectin and selenium sulphide shampoo.
June 2018 in “JoLS Journal of Life Sciences” The fermented mixture may help hair growth and has antioxidative benefits.
May 2013 in “International journal of innovative research and development” This article discusses a hypothetical model of androgenic hair trichophore composed of various chemical components, but it reports no new empirical findings; the authors emphasize the model's potential impact on hair cosmetics.
January 2023 in “Revista Eletrônica Acervo Saúde” This integrative literature review found that oral Minoxidil is a favorable alternative for individuals intolerant to topical application, effectively treating various forms of alopecia, though side effects like increased hair growth and minor dermatological reactions are noted.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” ZNF750 and MPZL3 are important in causing seborrheic dermatitis.
July 2023 in “Journal of ayurveda and integrated medical sciences” In a study of 50 healthy adults, Keshohills hair oil was shown to be effective in reducing hair loss and treating seborrheic dermatitis.
April 2021 in “Journal of the European Academy of Dermatology and Venereology” This corrigendum corrects the institutional affiliation of Flavio A. Cadegiani for several articles on COVID-19 and androgen-related treatments but reports no new results.
7 citations
,
June 2025 in “International Journal of Molecular Sciences” This review highlights that vitexin, a natural flavonoid derived from plants like mung bean, modulates critical cellular processes involved in cancer progression, suggesting its potential as a multi-target anticancer treatment in preclinical studies.
4 citations
,
March 2022 in “Journal of Cosmetic Dermatology” This study found that formulations containing saccharide isomerate significantly improved scalp flaking, sebum secretion, and transepidermal water loss compared to placebo in an adult Chinese population with dandruff.
October 2025 in “Records of Natural Products” This research found that kaempferol, a flavonoid from hair growth-promoting plants, significantly enhanced human dermal papilla cell proliferation and inhibited specific signaling pathways, outperforming minoxidil, with topical application in mice promoting hair growth and thickness, indicating potential as a natural hair loss treatment.
March 2024 in “Current materials science” This study explores the various properties of the flavonoid fisetin, highlighting its potential therapeutic applications due to its ability to modulate numerous biological pathways, suggesting benefits in conditions like inflammation, cancer, and neurodegenerative diseases.
45 citations
,
November 2024 in “International Journal of Molecular Sciences” This review discusses how various nutrients, such as flavonoids, probiotics, and omega-3 fatty acids, may support brain health by targeting stress-related pathways, potentially offering protective effects against neurodegenerative and psychiatric disorders through their roles in oxidative stress reduction and neuroinflammation regulation.
3 citations
,
June 2021 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” This review highlights phytochemicals, particularly flavonoids and phenolics, as potential supportive treatments for SARS-CoV-2 by interfering with viral proteins and providing anti-inflammatory effects; it suggests a foundation for future therapeutic and vaccine development efforts.
January 2026 in “Journal of Ethnopharmacology” This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.
This critical review highlights the anti-carcinogenic properties of luteolin, a plant flavonoid, and examines how encapsulating luteolin in nanoformulations may overcome its bioavailability challenges, potentially enhancing its effectiveness as a safer cancer treatment according to this source.
December 2023 in “Journal of ethnopharmacology” This study found that tribuloside, a flavonoid from Tribulus terrestris L., enhances melanin production in human melanocytes, zebrafish, and human skin samples without causing toxicity, potentially through inhibiting PDE to increase cAMP levels and promote the melanin biosynthesis pathway.
April 2017 in “Journal of Investigative Dermatology” This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.
27 citations
,
March 2024 in “Frontiers in Pharmacology” This review highlights the potential of natural product-derived compounds, such as flavonoids and alkaloids, to reverse multidrug resistance in tumors, emphasizing their role in regulating signaling pathways, proteins, and genes related to MDR, and aims to guide future research efforts in this area.
4 citations
,
August 2023 in “Italian Journal of Food Science” This study found that pretreatment combining maceration with press-shear force and moist heat significantly increased the total phenolic and flavonoid contents in galactagogue herbs like banana inflorescences and Thai ginger.
2 citations
,
September 2018 in “Walailak Journal of Science and Technology (WJST)” This study found that Thuja orientalis fruits have higher monoterpene, flavonoid, phenolic content, and antioxidant activity than leaves, suggesting potential value for the pharmaceutical industry.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, quercetin and kaempferol, two plant-derived flavonoids, showed stronger binding affinities to JAK3 kinase and moderate binding to 5-alpha reductase type 2, suggesting their potential as natural treatments for androgenetic alopecia, with quercetin demonstrating suitable properties for topical application.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study used molecular docking to analyze the binding affinities of quercetin and kaempferol, plant-derived flavonoids, showing they have promising interaction profiles with JAK3 kinase and moderate binding with 5-alpha reductase type 2, suggesting potential as topical treatments for androgenetic alopecia.
October 2025 in “Indonesian Journal of Pharmaceutical Science and Technology” This review highlights the significant antidiabetic activity of Allium ascalonicum (shallot), attributed to its flavonoid compounds like quercetin, in reducing blood glucose levels across various studies, while calling for further research to confirm its safety and efficacy as a diabetes treatment.