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This study found that supplementing young rats' diet with lactoflavin prevented cataract development, while a diet lacking all B vitamins, except flavin, led to cataracts and alopecia.

This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.

This study found that silibinin may promote hair growth by increasing proliferation and activating the AKT and Wnt/β-catenin signaling pathways in 3D cultured human dermal papilla spheroids.

This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.

This study found that baicalin activates Wnt/ß-catenin signaling in human dermal papilla cells, increasing alkaline phosphatase expression, growth factor expression, and promoting hair growth in mice.

This study found that flavonoids with two hydroxyl groups in their B-ring, such as sterubin and luteolin, supported the regeneration of pigmented hair after skin injury, unlike those with one hydroxyl group.

This study found that several local vegetables from Northern Thailand demonstrated significant antioxidant and 5α-reductase inhibitory activities, suggesting their potential for development into health-promoting products.

This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.

This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.

This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.

This study evaluated a herbal shampoo containing flavonoid glycosides from Dicerocaryum senecioides and found that it successfully treated T. tonsurans infections in children's scalp when used daily, demonstrating significant effectiveness compared to a placebo.

In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.

This study found that a 2.5% flavonoid-rich extract of Equisetum hyemale promoted hair growth in a rat model of chemically-induced alopecia, showing results comparable to 5% minoxidil.

This review discusses the role of flavonoids and Nod factors in the symbiosis between legumes and rhizobia and reports no new results; the authors argue this knowledge could enhance sustainable agriculture.

In this study, Eremochloa ophiuroides-derived fractions were found to significantly promote hair regrowth in a mouse model, demonstrating effects comparable to minoxidil and suggesting potential as natural hair growth agents through modulation of follicular activation markers and growth-regulatory factors.

This study highlighted the promising health benefits of taxifolin, a flavonoid with antioxidant, anti-inflammatory, and other protective effects found in foods like onions and milk thistle, though more research is needed to fully understand its mechanisms and safety for human therapeutic use.

In this study, DMC selectively eliminated senescent cells in old mice, prevented hair loss, improved motor coordination, and reduced senescence-associated secretory factors, suggesting its potential as a senolytic treatment.

The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.

This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.

This study found that a hair tonic formulated from green tea extract showed similar hair growth-promoting activity to 2% Minoxidil in rabbits, without causing skin irritation or bacterial contamination.

In this study, researchers found that in adult mice, new hair follicles with pigmentation can regenerate from the epidermis after skin wounding, aided by melanocyte stem cells moving from nearby existing hair follicles.

This study found that t-flavanone may promote hair growth in people with androgenic alopecia by enhancing hair anchoring strength and upregulating desmoglein expression in hair follicles over 30 weeks.

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.

This study suggests that silibinin may promote hair growth in 3D-cultured human dermal papilla spheroids by activating the Akt and Wnt/β-catenin signaling pathways.

This study found that Anigozanthos Flavidus flower extract may improve skin elasticity and reduce wrinkles by increasing essential extracellular matrix proteins in both in vitro and in vivo settings.

In a study involving adults with mild to moderate dandruff, researchers observed that post-hair wash interventions significantly reduced dandruff as measured by three assessment methods, showing substantial reliability and correlation, which supports their use in clinical settings for evaluating scalp dandruff treatments.

This study found that silver nanoparticles synthesized using Lens culinaris extract exhibited potent anticancer activity against MCF-7, HCT-116, and HepG2 cell lines and significant antimicrobial effects against Klebsiella pneumoniae and Acinetobacter baumannii.

In this laboratory study, researchers reported that Camellia sinensis seed flavonoids significantly reduced oxidative stress and inflammation in UV-irradiated skin cells by modulating key signaling pathways, highlighting its potential as a skincare ingredient for anti-inflammatory and anti-photoaging benefits.

This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.