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Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

HIV can cause unusual and severe skin problems that are hard to treat.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Erosive pustular dermatosis of the scalp is a type of skin inflammation often confused with other conditions, requiring continuous treatment.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.