research Metabolic Features of the Reproductive Phenotypes of Polycystic Ovary Syndrome
Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.
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research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research Theoretical Considerations in Laser Hair Removal
Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research The Use of a Transscrotal Testosterone Delivery System in the Treatment of Patients with Weight Loss Related to Human Immunodeficiency Virus Infection
The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.
research Premature Adrenarche: Early Maturation of Adrenal Glands in Children
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research Chaos and Antichaos in Pathology
Understanding chaos and control mechanisms in disease can improve diagnosis and prediction in medicine.
research Provision of Patient-Centered Transgender Care
The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.
research High Circulating Estrone and Low Testosterone Correlate with Adverse Clinical Outcomes in Men with Advanced Liver Disease
Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
research Insights Learned from L457(3.43)R, an Activating Mutant of the Human Lutropin Receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Sorafenib Combined with Hepatectomy in Patients with Intermediate-Stage and Advanced Hepatocellular Carcinoma
Sorafenib after liver surgery may increase survival for some liver cancer patients.
research Treating Psychogenic Nonepileptic Seizures: Easier Said Than Done
Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
research Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application
Improved finasteride formula allows slow, sustained release and better absorption for patients.
research Real-World Effectiveness, Safety, and Tolerability of Cetosomal Minoxidil 5% Alone and in Combination With Finasteride 0.1% in the Management of Androgenetic Alopecia
Cetosomal minoxidil alone and with finasteride is effective and well-tolerated for hair loss treatment.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation
Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
research Lichen Planus Pigmentosus and Its Variants: Review and Update
Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.
research Clinical and Microscopic Features of Generalized Discoid Lupus Erythematosus in Dogs (10 Cases)
Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
research Risks of Skin, Hair, and Nail Supplements
Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
research Engineered Exosomes Biopotentiated Hydrogel Promote Hair Follicle Growth via Reprogramming the Perifollicular Microenvironment
The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.
research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research Metabolic Syndrome: Myth or Reality in the Endocrinology Clinic
Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.
research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin
Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
research Development of a New GC-MS/MS Method for the Determination of Metformin in Human Hair
A new method was created to measure metformin in hair, showing potential for monitoring treatment and medical investigations.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research The Impact of COVID-19 on the Menstrual Cycle: A General Perspective
The combination tablet of finasteride and doxazosin works the same as taking each drug separately.
research Prevention and Treatment of Chemotherapy-Induced Alopecia
Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Recent Advances in Microneedle Composites for Biomedical Applications: Advanced Drug Delivery Technologies
Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.