December 2025 in “Antioxidants” This study reported that fermented yeast complex extract may promote hair regrowth by modulating antioxidative and anti-inflammatory pathways in dermal papilla cells and increasing hair follicle numbers in an animal model.
September 2025 in “Journal of Applied Biological Chemistry” In a laboratory study, Grateloupia elata extract demonstrated antioxidant and anti-aging effects by scavenging free radicals, inhibiting collagenase and elastase, increasing procollagen production, and reducing MMP-1 secretion, suggesting its potential use in functional cosmetics.
April 2025 in “Antioxidants” In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
March 2025 in “Regenerative Therapy” This study suggests that SACM may enhance hair growth more effectively than non-treated ACM, highlighting the potential of S. maxima as a promising agent for use in pharmaceutical and cosmeceutical industries.
April 2011 in “한국생물공학회 학술대회” This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.
13 citations
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February 2023 in “Pharmaceutics” This review outlines strategies for regulating macrophage response using bioactive materials to enhance wound healing, focusing on extracellular matrix-based scaffolds and nanofibrous composites, but reports no new clinical results.
2 citations
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January 2024 in “Pharmaceuticals” This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.
47 citations
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July 2005 in “European Journal of Cell Biology” Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
November 2022 in “Journal of Investigative Dermatology” This study found that marine-derived collagen peptides slightly promoted hair matrix proliferation and prolonged hair growth phase in human hair follicles ex vivo, suggesting potential benefits for hair loss treatment.
182 citations
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November 2018 in “Cosmetics” This article reviews the empirical use of algae in traditional remedies and highlights the need for scientific understanding of algae's bioactive compounds used in cosmetics without providing new experimental results.
18 citations
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December 2021 in “Foods” This study explores the potential of seaweeds as a source of bioactive compounds for food, cosmetics, and medical applications, while highlighting concerns about toxic element accumulation and suggesting purification and nanoencapsulation techniques to enhance safety and stability.
8 citations
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November 2019 in “Clinical Science” This study found that higher levels of DHA from omega-3 fatty acids delayed inflammation resolution and impaired wound healing quality in both transgenic mice and wild-type mice supplemented with DHA.
5 citations
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December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
3 citations
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July 2025 in “Reproductive Biology and Endocrinology” This study found that chromium, inositol, and Omega-3 are beneficial for improving lipid profiles in women with PCOS, and various supplements help alleviate other symptoms.
August 2026 in “Biology Bulletin Reviews” This study found that extracts from Avicennia marina, Moringa oleifera, and Calotropis procera demonstrated strong antibacterial, antioxidant, and hair-growth-promoting properties, with A. marina showing the most pronounced effects.
November 2024 in “VITEK Bidang Kedokteran Hewan” In this case study, treatment using ivermectin, antihistamines, topical antibiotics, and supplements resulted in clinical recovery from scabies-related symptoms in a domestic male cat, showing significant reduction in itching and skin lesions by the seventh day.
July 2023 in “International Journal of Cosmetic Science” This article reviews how biopolymers are utilized in cosmetics, highlighting their biodegradable and non-toxic properties, recent structural developments, novel applications, and safety considerations in the formulation of skin, hair, and oral care products.
This article discusses the impact of hyperandrogenism in polycystic ovary syndrome on women's physical and mental health, but it reports no new experimental findings.
June 2023 in “JAAD international” This report highlights that 49.4% of U.S. patients with skin issues use complementary and alternative medicine (CAM), with 6% leveraging it specifically for their skin conditions, including treatments like herbal, vitamin, and mineral supplementation for alopecia.
January 2023 in “Biomaterials Science” This study suggests that incorporating matrisomal components into biomaterials could enhance skin wound healing in mammals that do not naturally regenerate tissues like the axolotl and Acomys.
2 citations
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August 2025 in “Pharmaceutics” This review compares DNA-derived biopolymers, PN and PDRN, in dermatology, emphasizing their distinct molecular characteristics and roles, and reports no new clinical results.
76 citations
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February 2024 in “International Journal of Molecular Sciences” This review discusses the growing importance of hydrogel scaffolds in skin wound healing, highlighting their unique properties and recent advancements in their use for treating difficult tissue damage, particularly within tissue engineering.
21 citations
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November 2021 in “Biomolecules” This review compiles information on traditional uses, phytoconstituents, and biological activities of Eclipta prostrata but reports no new experimental results; the authors call for more studies to understand its pharmacological mechanisms.
16 citations
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March 2024 in “International Journal of Molecular Sciences” This review highlights how natural compounds can enhance wound healing by influencing fibroblast behavior and discusses innovative biomimetic engineering and delivery methods. This source emphasizes combining traditional and modern approaches for effective and scar-free healing, while noting challenges in clinical translation.
15 citations
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March 2021 in “EMBO Reports” PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.
6 citations
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August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.
1 citations
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April 2023 in “Science Advances” This study found that sustained ERK activity during tissue regeneration in spiny mice is linked to fibroblast growth factor and ErbB signaling, while inhibiting ERK shifted regeneration toward scarring.
This review reports that oral collagen peptide supplements may improve skin elasticity, hydration, and wrinkle appearance while also supporting hair and nail health and wound healing, but emphasizes the need for longer, high-quality studies due to current research limitations and variability in findings.
In this study, clove leaf ethanol extract shampoo at 15% concentration effectively promoted hair growth in male white rats, though it was less effective than 5% minoxidil.
This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.