March 2026 in “International Journal of Molecular Sciences” This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
February 2025 in “Applied Sciences” This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.
February 2025 in “Frontiers in Veterinary Science” This study found that keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide promoted β-catenin nuclear translocation and increased gene expression related to hair regeneration in canine and cat skin cell lines, suggesting these nutrients may help improve hair regeneration in pets.
October 2023 in “Arab Gulf journal of scientific research” This study found that adding Cinnamomum zeylanicum bark extract to a powder shampoo formulation significantly improved antioxidant activity without affecting its cleansing ability, although its clinical effectiveness remains to be tested.
May 2020 in “International journal of current microbiology and applied sciences” This case report describes a 3-year-old pug with mixed Demodicosis and Staphylococcal infections that recovered completely after two months of combined antiparasitic, antibacterial, anti-inflammatory treatment, and supportive therapy.
August 2019 in “Research Square (Research Square)” This study explored how long non-coding RNA mediates the effects of FGF5 on the hair follicle development and villus growth of Liaoning cashmere goats.
June 2011 in “Journal of medicine and life science” In this cell study, seaweed extract from Hizkia fusiforme significantly increased the proliferation of dermal papilla cells, suggesting potential for promoting hair growth.
February 2023 in “Frontiers in Pharmacology” This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.
85 citations
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December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
5 citations
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November 2024 in “Cells” This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.
research Acne
4 citations
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January 2019 This analysis examines acne vulgaris using an integrative approach, highlighting its links with psychopathology, lifestyle, and diet, but reports no new results.
4 citations
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October 2021 in “Journal of Cellular and Molecular Medicine” This study observed that mature neutrophils and their extracellular traps inhibit wound-induced hair follicle neogenesis in mice, despite being stimulated by pro-regenerative cues.
August 2023 in “Repository of the University of Primorsk (University of Primorska)” A Western diet may increase acne risk, while a Mediterranean diet and certain supplements can help reduce it.
July 2024 in “International journal of agriculture and food sciences research.” This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.
September 2023 in “Jurnal Ilmu Kesehatan Hewan” This case report describes a Balinese breed dog diagnosed with demodecosis and malasseziosis, which improved after 30 days of treatment including amitraz, ketoconazole, and supportive therapies. The findings suggest that consistent treatment and environmental management can aid in recovery from these skin conditions in dogs.
13 citations
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January 2016 in “Journal of cosmetology & trichology” This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.
9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
5 citations
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October 2025 in “International Journal of Nanomedicine” This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.
January 2026 in “Journal of Biomaterials Applications” This study found that a fish skin-derived acellular dermal matrix improved wound healing in diabetic rats, showing faster closure rates and enhanced tissue regeneration compared to commercial alternatives.
188 citations
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December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
June 2023 in “Antioxidants” This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
95 citations
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February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
87 citations
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September 2019 in “Nature Communications” In this study, researchers identified that upon tissue injury in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state with SOX11 and SOX4 playing a central role in modulating epidermal development and cell migration genes.
66 citations
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May 2021 in “Science Advances” In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.
55 citations
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April 2018 in “Advanced Healthcare Materials” This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.
49 citations
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February 2025 in “Science Advances” This review discusses the potential of biomimetic synthetic vesicles to advance precision diagnostics and medicine by combining the beneficial properties of naturally occurring extracellular vesicles and synthetic nanoparticles, although no new clinical results are reported.
35 citations
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May 2021 in “Nature communications” This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.
26 citations
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September 2023 in “Bioengineered” This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.
24 citations
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June 2021 in “Annals of Translational Medicine” This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.