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ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.

Epiduo® is an effective first-line acne treatment that reduces inflammation and combats antibiotic resistance.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

The combination of TACE and Donafenib is effective and tolerable for treating unresectable liver cancer.

Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Use minoxidil or finasteride first, then try HairMax LaserComb if needed.

The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.

Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.

Use topical retinoids for most acne cases, sometimes combined with other treatments.

Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.

Topical corticosteroids are the best initial treatment for children's alopecia areata.

Traditional treatment for pediatric alopecia areata is most effective and should be first choice.

Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.

Alopecia areata can be managed with various treatments, and severe cases should be referred to dermatologists.

Use finasteride, dutasteride, and minoxidil for hair loss treatment.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Oral retinoids may help some patients with hard-to-treat lichen planopilaris, but more research is needed.

Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.

Scarring alopecia causes permanent hair loss, and treatment aims to reduce inflammation and stop it from getting worse.

Different treatments for skin conditions were found to be effective and generally safe, with biologics recommended as the first choice for generalized pustular psoriasis.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.